The adenohypophysis of the Australian lungfish, Neoceratodus forsteri-An immunocytological study

Jean M. P. Joss*, Mandy Beshaw, Susan Williamson, Jane Trimble, Robert M. Dores

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    23 Citations (Scopus)

    Abstract

    The cell types in the adenohypophysis of Neoceratodus resemble closely those already described for Lepidosiren and Protopterus. Four of these were immunocytochemically identified as prolactin cells, gonadotropes, corticotropes, and melanotropes. Antiserum to bullfrog growth hormone could not distinguish between prolactin cells and somatotropes. Anti-bullfrog prolactin, however, did selectively stain the prolactin cells, which allowed the identification of the somatotropes. The presumptive thyrotropes, as the only remaining cell type in the pars distalis, can then be tentatively identified by default. Likewise a PAS-positive cell type in the pars intermedia had no immunoreactivity to any of the antisera used. The functional significance of this cell remains to be demonstrated. One of the more unexpected findings was the presence of large numbers of cells immunoreactive to α-MSH in the proximal pars distalis. The implications of the presence of these cells in adult lungfish are discussed. The distribution of cell types within the pituitary of Neoceratodus showed more regionalization than is present in the other lungfish and corresponded more closely to that described for primitive actinopterygian fish. The general structure of the pituitary of Neoceratodus also resembled primitive actinopterygian fish more closely than it did amphibians, unlike the pituitaries of Lepidosiren and Protopterus. The evolutionary significance of this is also discussed.

    Original languageEnglish
    Pages (from-to)274-287
    Number of pages14
    JournalGeneral and Comparative Endocrinology
    Volume80
    Issue number2
    DOIs
    Publication statusPublished - 1990

    Fingerprint

    Dive into the research topics of 'The adenohypophysis of the Australian lungfish, Neoceratodus forsteri-An immunocytological study'. Together they form a unique fingerprint.

    Cite this