The assembly of a photoluminescent nanocomplex based on upconversion nanoparticles

S. Shanwar; L. Liang; A. V. Nechaev; I. V. Balalaeva; V. A. Vodeneev; A. V. Zvyagin; E. L. Guryev

doi:10.24411/2500-2295-2020-10013

The assembly of a photoluminescent nanocomplex based on upconversion nanoparticles

S. Shanwar, L. Liang, A. V. Nechaev, I. V. Balalaeva, V. A. Vodeneev, A. V. Zvyagin, E. L. Guryev

ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP)

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

20 Downloads (Pure)

Abstract

Over the past two decades, developments in the field of nanobiomedicine have come a long way despite the unresolved hindrances. The creation and development of effective theranostic agents based on nanomaterials are urgent needs of modern medicine. Upconversion nanoparticles (UCNP) appear to be the most promising agents for developing theranostics due to their unique optical properties. There has been extensive research on new approaches to obtain stable colloids capable of prolonged circulation in the bloodstream, particularly with bovine serum albumin (BSA). The present work contributes to solving the problem of obtaining stable agents based on UCNP by coating water-soluble UCNP-NOBF4 with a stable protein corona layer of BSA. The assembled nanocomplex is promising for usage as a diagnostic agent and is set for further investigation.

Original language	English
Pages (from-to)	42-48
Number of pages	7
Journal	Opera Medica et Physiologica
Volume	7
Issue number	4
DOIs	https://doi.org/10.24411/2500-2295-2020-10013
Publication status	Published - Dec 2020

Bibliographical note

Copyright © 2020, Lobachevsky State University of Nizhny Novgorod. All rights reserved. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

Bovine serum albumin
Protein corona
Upconversion nanoparticle

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10.24411/2500-2295-2020-10013Licence: CC BY

Publisher version (open access)Final published version, 615 KBLicence: CC BY

http://operamedphys.org/content/assembly-photoluminescent-nanocomplex-based-upconversion-nanoparticles

Cite this

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abstract = "Over the past two decades, developments in the field of nanobiomedicine have come a long way despite the unresolved hindrances. The creation and development of effective theranostic agents based on nanomaterials are urgent needs of modern medicine. Upconversion nanoparticles (UCNP) appear to be the most promising agents for developing theranostics due to their unique optical properties. There has been extensive research on new approaches to obtain stable colloids capable of prolonged circulation in the bloodstream, particularly with bovine serum albumin (BSA). The present work contributes to solving the problem of obtaining stable agents based on UCNP by coating water-soluble UCNP-NOBF4 with a stable protein corona layer of BSA. The assembled nanocomplex is promising for usage as a diagnostic agent and is set for further investigation.",

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AU - Vodeneev, V. A.

AU - Zvyagin, A. V.

AU - Guryev, E. L.

N1 - Copyright © 2020, Lobachevsky State University of Nizhny Novgorod. All rights reserved. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

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AB - Over the past two decades, developments in the field of nanobiomedicine have come a long way despite the unresolved hindrances. The creation and development of effective theranostic agents based on nanomaterials are urgent needs of modern medicine. Upconversion nanoparticles (UCNP) appear to be the most promising agents for developing theranostics due to their unique optical properties. There has been extensive research on new approaches to obtain stable colloids capable of prolonged circulation in the bloodstream, particularly with bovine serum albumin (BSA). The present work contributes to solving the problem of obtaining stable agents based on UCNP by coating water-soluble UCNP-NOBF4 with a stable protein corona layer of BSA. The assembled nanocomplex is promising for usage as a diagnostic agent and is set for further investigation.

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The assembly of a photoluminescent nanocomplex based on upconversion nanoparticles

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Keywords

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