The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium

Jonathan A. Eisen; Karen E. Nelson; Ian T. Paulsen; John F. Heidelberg; Martin Wu; Robert J. Dodson; Robert Deboy; Michelle L. Gwinn; William C. Nelson; Daniel H. Haft; Erin K. Hickey; Jeremy D. Peterson; A. Scott Durkin; James L. Kolonay; Fan Yang; Ingeborg Holt; Lowell A. Umayam; Tanya Mason; Michael Brenner; Terrance P. Shea; Debbie Parksey; William C. Nierman; Tamara V. Feldblyum; Cheryl L. Hansen; M. Brook Craven; Diana Radune; Jessica Vamathevan; Hoda Khouri; Owen White; Tanja M. Gruber; Karen A. Ketchum; J. Craig Venter; Hervé Tettelin; Donald A. Bryant; Claire M. Fraser

doi:10.1073/pnas.132181499

The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium

Jonathan A. Eisen^*, Karen E. Nelson, Ian T. Paulsen, John F. Heidelberg, Martin Wu, Robert J. Dodson, Robert Deboy, Michelle L. Gwinn, William C. Nelson, Daniel H. Haft, Erin K. Hickey, Jeremy D. Peterson, A. Scott Durkin, James L. Kolonay, Fan Yang, Ingeborg Holt, Lowell A. Umayam, Tanya Mason, Michael Brenner, Terrance P. SheaDebbie Parksey, William C. Nierman, Tamara V. Feldblyum, Cheryl L. Hansen, M. Brook Craven, Diana Radune, Jessica Vamathevan, Hoda Khouri, Owen White, Tanja M. Gruber, Karen A. Ketchum, J. Craig Venter, Hervé Tettelin, Donald A. Bryant, Claire M. Fraser

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

300 Citations (Scopus)

Abstract

The complete genome of the green-sulfur eubacterium Chlorobium tepidum TLS was determined to be a single circular chromosome of 2,154,946 bp. This represents the first genome sequence from the phylum Chlorobia, whose members perform anoxygenic photosynthesis by the reductive tricarboxylic acid cycle. Genome comparisons have identified genes in C tepidum that are highly conserved among photosynthetic species. Many of these have no assigned function and may play novel roles in photosynthesis or photobiology. Phylogenomic analysis reveals likely duplications of genes involved in biosynthetic pathways for photosynthesis and the metabolism of sulfur and nitrogen as well as strong similarities between metabolic processes in C tepidum and many Archaeal species.

Original language	English
Pages (from-to)	9509-9514
Number of pages	6
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	99
Issue number	14
DOIs	https://doi.org/10.1073/pnas.132181499
Publication status	Published - 9 Jul 2002
Externally published	Yes

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Eisen, J. A., Nelson, K. E., Paulsen, I. T., Heidelberg, J. F., Wu, M., Dodson, R. J., Deboy, R., Gwinn, M. L., Nelson, W. C., Haft, D. H., Hickey, E. K., Peterson, J. D., Durkin, A. S., Kolonay, J. L., Yang, F., Holt, I., Umayam, L. A., Mason, T., Brenner, M., ... Fraser, C. M. (2002). The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium. Proceedings of the National Academy of Sciences of the United States of America, 99(14), 9509-9514. https://doi.org/10.1073/pnas.132181499

@article{aa452d9c70e04125b2c8261d844d2b54,

title = "The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium",

abstract = "The complete genome of the green-sulfur eubacterium Chlorobium tepidum TLS was determined to be a single circular chromosome of 2,154,946 bp. This represents the first genome sequence from the phylum Chlorobia, whose members perform anoxygenic photosynthesis by the reductive tricarboxylic acid cycle. Genome comparisons have identified genes in C tepidum that are highly conserved among photosynthetic species. Many of these have no assigned function and may play novel roles in photosynthesis or photobiology. Phylogenomic analysis reveals likely duplications of genes involved in biosynthetic pathways for photosynthesis and the metabolism of sulfur and nitrogen as well as strong similarities between metabolic processes in C tepidum and many Archaeal species.",

author = "Eisen, {Jonathan A.} and Nelson, {Karen E.} and Paulsen, {Ian T.} and Heidelberg, {John F.} and Martin Wu and Dodson, {Robert J.} and Robert Deboy and Gwinn, {Michelle L.} and Nelson, {William C.} and Haft, {Daniel H.} and Hickey, {Erin K.} and Peterson, {Jeremy D.} and Durkin, {A. Scott} and Kolonay, {James L.} and Fan Yang and Ingeborg Holt and Umayam, {Lowell A.} and Tanya Mason and Michael Brenner and Shea, {Terrance P.} and Debbie Parksey and Nierman, {William C.} and Feldblyum, {Tamara V.} and Hansen, {Cheryl L.} and Craven, {M. Brook} and Diana Radune and Jessica Vamathevan and Hoda Khouri and Owen White and Gruber, {Tanja M.} and Ketchum, {Karen A.} and Venter, {J. Craig} and Herv{\'e} Tettelin and Bryant, {Donald A.} and Fraser, {Claire M.}",

year = "2002",

month = jul,

day = "9",

doi = "10.1073/pnas.132181499",

language = "English",

volume = "99",

pages = "9509--9514",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

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Eisen, JA, Nelson, KE, Paulsen, IT, Heidelberg, JF, Wu, M, Dodson, RJ, Deboy, R, Gwinn, ML, Nelson, WC, Haft, DH, Hickey, EK, Peterson, JD, Durkin, AS, Kolonay, JL, Yang, F, Holt, I, Umayam, LA, Mason, T, Brenner, M, Shea, TP, Parksey, D, Nierman, WC, Feldblyum, TV, Hansen, CL, Craven, MB, Radune, D, Vamathevan, J, Khouri, H, White, O, Gruber, TM, Ketchum, KA, Venter, JC, Tettelin, H, Bryant, DA & Fraser, CM 2002, 'The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium', Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 14, pp. 9509-9514. https://doi.org/10.1073/pnas.132181499

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T1 - The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium

AU - Eisen, Jonathan A.

AU - Nelson, Karen E.

AU - Paulsen, Ian T.

AU - Heidelberg, John F.

AU - Wu, Martin

AU - Dodson, Robert J.

AU - Deboy, Robert

AU - Gwinn, Michelle L.

AU - Nelson, William C.

AU - Haft, Daniel H.

AU - Hickey, Erin K.

AU - Peterson, Jeremy D.

AU - Durkin, A. Scott

AU - Kolonay, James L.

AU - Yang, Fan

AU - Holt, Ingeborg

AU - Umayam, Lowell A.

AU - Mason, Tanya

AU - Brenner, Michael

AU - Shea, Terrance P.

AU - Parksey, Debbie

AU - Nierman, William C.

AU - Feldblyum, Tamara V.

AU - Hansen, Cheryl L.

AU - Craven, M. Brook

AU - Radune, Diana

AU - Vamathevan, Jessica

AU - Khouri, Hoda

AU - White, Owen

AU - Gruber, Tanja M.

AU - Ketchum, Karen A.

AU - Venter, J. Craig

AU - Tettelin, Hervé

AU - Bryant, Donald A.

AU - Fraser, Claire M.

PY - 2002/7/9

Y1 - 2002/7/9

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AB - The complete genome of the green-sulfur eubacterium Chlorobium tepidum TLS was determined to be a single circular chromosome of 2,154,946 bp. This represents the first genome sequence from the phylum Chlorobia, whose members perform anoxygenic photosynthesis by the reductive tricarboxylic acid cycle. Genome comparisons have identified genes in C tepidum that are highly conserved among photosynthetic species. Many of these have no assigned function and may play novel roles in photosynthesis or photobiology. Phylogenomic analysis reveals likely duplications of genes involved in biosynthetic pathways for photosynthesis and the metabolism of sulfur and nitrogen as well as strong similarities between metabolic processes in C tepidum and many Archaeal species.

UR - http://www.scopus.com/inward/record.url?scp=0037047102&partnerID=8YFLogxK

U2 - 10.1073/pnas.132181499

DO - 10.1073/pnas.132181499

M3 - Article

C2 - 12093901

AN - SCOPUS:0037047102

SN - 0027-8424

VL - 99

SP - 9509

EP - 9514

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 14

ER -

The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium

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