TY - JOUR
T1 - The complexity and fractal geometry of nuclear medicine images
AU - Grizzi, Fabio
AU - Castello, Angelo
AU - Qehajaj, Dorina
AU - Russo, Carlo
AU - Lopci, Egesta
PY - 2019/6
Y1 - 2019/6
N2 - Irregularity in shape and behavior is the main feature of every anatomical system, including human organs, tissues, cells, and sub-cellular entities. It has been shown that this property cannot be quantified by means of the classical Euclidean geometry, which is only able to describe regular geometrical objects. In contrast, fractal geometry has been widely applied in several scientific fields. This rapid growth has also produced substantial insights in the biomedical imaging. Consequently, particular attention has been given to the identification of pathognomonic patterns of “shape” in anatomical entities and their changes from natural to pathological states. Despite the advantages of fractal mathematics and several studies demonstrating its applicability to oncological research, many researchers and clinicians remain unaware of its potential. Therefore, this review aims to summarize the complexity and fractal geometry of nuclear medicine images.
AB - Irregularity in shape and behavior is the main feature of every anatomical system, including human organs, tissues, cells, and sub-cellular entities. It has been shown that this property cannot be quantified by means of the classical Euclidean geometry, which is only able to describe regular geometrical objects. In contrast, fractal geometry has been widely applied in several scientific fields. This rapid growth has also produced substantial insights in the biomedical imaging. Consequently, particular attention has been given to the identification of pathognomonic patterns of “shape” in anatomical entities and their changes from natural to pathological states. Despite the advantages of fractal mathematics and several studies demonstrating its applicability to oncological research, many researchers and clinicians remain unaware of its potential. Therefore, this review aims to summarize the complexity and fractal geometry of nuclear medicine images.
UR - http://www.scopus.com/inward/record.url?scp=85049780420&partnerID=8YFLogxK
U2 - 10.1007/s11307-018-1236-5
DO - 10.1007/s11307-018-1236-5
M3 - Article
C2 - 30003453
AN - SCOPUS:85049780420
VL - 21
SP - 401
EP - 409
JO - Molecular Imaging and Biology
JF - Molecular Imaging and Biology
SN - 1536-1632
IS - 3
ER -