The dark side of the (half) moon

Francesco Pellegrini*, Altin Stafa, Daniela Bonsanto, Clare L. Fraser

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 71-year-old man was referred to neuro-ophthalmology for evaluation of reading problems associated with pituitary adenoma. Perimetry showed a right temporal crescent syndrome (“half moon” syndrome) suggesting left occipital disease. Cranial magnetic resonance imaging, electroencephalogram, and cerebrospinal fluid examination (14-3-3 protein) were consistent with a diagnosis of Creutzfeldt-Jakob disease. His neurologic condition rapidly deteriorated with memory problems, myoclonus, and apathy followed by death, 4 months later. This case shows how visual problems may be the first manifestation of this rare prion disease (Heidenhain variant of Creutzfeldt-Jakob disease).

Original languageEnglish
Pages (from-to)381-385
Number of pages5
JournalSurvey of Ophthalmology
Volume65
Issue number3
DOIs
Publication statusPublished - 1 May 2020
Externally publishedYes

Keywords

  • half moon syndrome
  • Heidenhain variant of Creutzfeldt-Jakob disease
  • temporal crescent syndrome

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    Pellegrini, F., Stafa, A., Bonsanto, D., & Fraser, C. L. (2020). The dark side of the (half) moon. Survey of Ophthalmology, 65(3), 381-385. https://doi.org/10.1016/j.survophthal.2019.02.001