The dark side of the (half) moon

Francesco Pellegrini; Altin Stafa; Daniela Bonsanto; Clare L. Fraser

doi:10.1016/j.survophthal.2019.02.001

The dark side of the (half) moon

Francesco Pellegrini^*, Altin Stafa, Daniela Bonsanto, Clare L. Fraser

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

A 71-year-old man was referred to neuro-ophthalmology for evaluation of reading problems associated with pituitary adenoma. Perimetry showed a right temporal crescent syndrome (“half moon” syndrome) suggesting left occipital disease. Cranial magnetic resonance imaging, electroencephalogram, and cerebrospinal fluid examination (14-3-3 protein) were consistent with a diagnosis of Creutzfeldt-Jakob disease. His neurologic condition rapidly deteriorated with memory problems, myoclonus, and apathy followed by death, 4 months later. This case shows how visual problems may be the first manifestation of this rare prion disease (Heidenhain variant of Creutzfeldt-Jakob disease).

Original language	English
Pages (from-to)	381-385
Number of pages	5
Journal	Survey of Ophthalmology
Volume	65
Issue number	3
DOIs	https://doi.org/10.1016/j.survophthal.2019.02.001
Publication status	Published - 1 May 2020
Externally published	Yes

Keywords

half moon syndrome
Heidenhain variant of Creutzfeldt-Jakob disease
temporal crescent syndrome

Access to Document

10.1016/j.survophthal.2019.02.001

Link to publication in Scopus

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title = "The dark side of the (half) moon",

abstract = "A 71-year-old man was referred to neuro-ophthalmology for evaluation of reading problems associated with pituitary adenoma. Perimetry showed a right temporal crescent syndrome (“half moon” syndrome) suggesting left occipital disease. Cranial magnetic resonance imaging, electroencephalogram, and cerebrospinal fluid examination (14-3-3 protein) were consistent with a diagnosis of Creutzfeldt-Jakob disease. His neurologic condition rapidly deteriorated with memory problems, myoclonus, and apathy followed by death, 4 months later. This case shows how visual problems may be the first manifestation of this rare prion disease (Heidenhain variant of Creutzfeldt-Jakob disease).",

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AU - Stafa, Altin

AU - Bonsanto, Daniela

AU - Fraser, Clare L.

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AB - A 71-year-old man was referred to neuro-ophthalmology for evaluation of reading problems associated with pituitary adenoma. Perimetry showed a right temporal crescent syndrome (“half moon” syndrome) suggesting left occipital disease. Cranial magnetic resonance imaging, electroencephalogram, and cerebrospinal fluid examination (14-3-3 protein) were consistent with a diagnosis of Creutzfeldt-Jakob disease. His neurologic condition rapidly deteriorated with memory problems, myoclonus, and apathy followed by death, 4 months later. This case shows how visual problems may be the first manifestation of this rare prion disease (Heidenhain variant of Creutzfeldt-Jakob disease).

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