The EcoCyc and MetaCyc databases

Peter D. Karp*, Monica Riley, Milton Saier, Ian T. Paulsen, Suzanne M. Paley, Alida Pellegrini-Toole

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

214 Citations (Scopus)


EcoCyc is an organism-specific Pathway/Genome Database that describes the metabolic and signal-transduction pathways of Escherichia coli, its enzymes, and - a new addition - its transport proteins. MetaCyc is a new metabolic-pathway database that describes pathways and enzymes of many different organisms, with a microbial focus. Both databases are queried using the Pathway Tools graphical user interface, which provides a wide variety of query operations and visualization tools. EcoCyc and MetaCyc are available at

Original languageEnglish
Pages (from-to)56-59
Number of pages4
JournalNucleic Acids Research
Issue number1
Publication statusPublished - 1 Jan 2000
Externally publishedYes


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