The Effect of time domain pose filtering on accuracy of small marker based motion correction in awake animal PET

Andre Kyme, Julian Maclaren, Steven Meikle, Clive Baldock, Roger Fulton

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contribution

8 Citations (Scopus)

Abstract

Optical motion tracking based on stereo geometry is useful in medical imaging applications to provide input for downstream processing tasks such as motion compensation. For tracking markers containing closely spaced target points, pose measurements exhibit greater jitter than for markers with larger distributions of target points. This is especially true for out-of-plane rotational motion. Three time-domain filtering techniques for small markers were considered with the aim of improving motion-corrected positron emission tomography (PET) studies of conscious rats: a finite impulse response (FIR) pose filter, Kalman filter, and Kalman smoother. Actual measured rat head motion was applied to a phantom using a precise, 6-axis robot. Motion was measured using a tracking system with both large and small markers and both sets of data, with and without filtering applied, were used for motion correction. Correction based on the large marker resulted in the best agreement with a motion-free reference image. Blurring and degradation were evident when the small marker data were unfiltered prior to motion correction. Image contrast, resolution and peak activity concentrations were all improved using the FIR filter. The Kalman filters did not improve the correction, appearing to over-smooth. This would likely be improved with pose-by-pose noise modeling rather than using an average noise estimate as was done here. In conclusion, the results emphasize the importance of filtering noisy motion data derived from small markers in order to obtain more robust estimates of pose for motion correction.
Original languageEnglish
Title of host publicationIEEE Nuclear Science Symposium and Medical Imaging Conference Record
Subtitle of host publicationNSS/MIC 2011, 23-29 October 2011, Valencia, Spain
Place of PublicationPiscataway, NJ
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Pages2290-2294
Number of pages5
ISBN (Print)9781467301183
DOIs
Publication statusPublished - 2012
Externally publishedYes
EventIEEE Nuclear Science Symposium and Medical Imaging Conference - Valencia, Spain
Duration: 23 Oct 201129 Oct 2011

Conference

ConferenceIEEE Nuclear Science Symposium and Medical Imaging Conference
CityValencia, Spain
Period23/10/1129/10/11

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    Kyme, A., Maclaren, J., Meikle, S., Baldock, C., & Fulton, R. (2012). The Effect of time domain pose filtering on accuracy of small marker based motion correction in awake animal PET. In IEEE Nuclear Science Symposium and Medical Imaging Conference Record: NSS/MIC 2011, 23-29 October 2011, Valencia, Spain (pp. 2290-2294). Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE). https://doi.org/10.1109/NSSMIC.2011.6153864