The effectiveness of exercise as treatment for vasomotor menopausal symptoms: Randomised controlled trial

A. J. Daley*, A. Thomas, A. K. Roalfe, H. Stokes-Lampard, S. Coleman, M. Rees, M. S. Hunter, C. Macarthur

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

48 Citations (Scopus)


Objective To investigate the effectiveness of exercise as treatment for vasomotor menopausal symptoms. Design Three-group randomised controlled trial, two exercise interventions and a control group. Setting Primary Care, West Midlands UK. Population Perimenopausal and postmenopausal women experiencing at least five hot flushes/night sweats per day and not taken MHT in previous 3 months were recruited from 23 general practices. Methods Participants in both exercise interventions groups were offered two face-to-face consultations with a physical activity facilitator to support engagement in regular exercise. In addition, one exercise group received a menopause-specific information DVD and written materials to encourage regular exercise and the other exercise group was offered the opportunity to attend exercise social support groups in their communities. Interventions lasted 6 months. Main outcome measure The primary outcome was frequency of hot flushes/night sweats at 6-month up. Results Two hundred and sixty-one women were randomised (n = 87 per group). Neither of the exercise intervention groups reported significantly less frequent hot flushes/night sweats per week than controls (exercise-DVD versus control: -8.9, 95% CI -20.0 to 2.2; exercise-social support versus control: -5.2, 95% CI -16.7 to 6.3). Conclusions This trial indicates that exercise is not an effective treatment for hot flushes/night sweats. Contrary to current clinical guidance, women should not be advised that exercise will relieve their vasomotor menopausal symptoms.

Original languageEnglish
Pages (from-to)565-575
Number of pages11
JournalBJOG: An International Journal of Obstetrics and Gynaecology
Issue number4
Early online date17 Dec 2014
Publication statusPublished - 1 Mar 2015


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