The functional influence of breast implant outer shell morphology on bacterial attachment and growth

Phoebe Jones, Maria Mempin, Honghua Hu, Durdana Chowdhury, Matthew Foley, Rodney Cooter, William P. Adams, Karen Vickery, Anand K. Deva

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: The introduction of texture to the outer shell of breast implants was aimed at increasing tissue incorporation and reducing capsular contracture. It has also been shown that textured surfaces promote a higher growth of bacteria and are linked to the development of breast implant-associated anaplastic large cell lymphoma. Methods: The authors aimed to measure the surface area and surface roughness of 11 available implants. In addition, the authors aimed to subject these implant shells to an in vitro bacterial attachment assay with four bacterial pathogens (Staphylococcus epidermidis, S. aureus, Pseudomonas aeruginosa, and Ralstonia pickettii) and study the relationship among surface area, surface roughness, and bacterial growth. Results: Surface area measurement showed grouping of implants into high, intermediate, low, and minimal. Surface roughness showed a correlation with surface area. The in vitro assay showed a significant linear relationship between surface area and bacterial attachment/growth. The high surface area/roughness implant texture grew significantly more bacteria at 24 hours, whereas the minimal surface area/roughness implant textures grew significantly fewer bacteria of all types at 24 hours. For implants with intermediate and low surface areas, some species differences were observed, indicating possible affinity of specific bacterial species to surface morphology. Conclusions: Implant shells should be reclassified using surface area/roughness into four categories (high, intermediate, low, and minimal). This classification is superior to the use of descriptive terms such as macrotexture, microtexture, and nanotexture, which are not well correlated with objective measurement and/or functional outcomes.

LanguageEnglish
Pages837-849
Number of pages13
JournalPlastic and reconstructive surgery
Volume142
Issue number4
DOIs
Publication statusPublished - 1 Oct 2018

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Breast Implants
Bacteria
Ralstonia pickettii
Growth
Anaplastic Large-Cell Lymphoma
Staphylococcus epidermidis
Contracture
Pseudomonas aeruginosa
In Vitro Techniques

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Jones, Phoebe ; Mempin, Maria ; Hu, Honghua ; Chowdhury, Durdana ; Foley, Matthew ; Cooter, Rodney ; Adams, William P. ; Vickery, Karen ; Deva, Anand K. / The functional influence of breast implant outer shell morphology on bacterial attachment and growth. In: Plastic and reconstructive surgery. 2018 ; Vol. 142, No. 4. pp. 837-849.
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abstract = "Background: The introduction of texture to the outer shell of breast implants was aimed at increasing tissue incorporation and reducing capsular contracture. It has also been shown that textured surfaces promote a higher growth of bacteria and are linked to the development of breast implant-associated anaplastic large cell lymphoma. Methods: The authors aimed to measure the surface area and surface roughness of 11 available implants. In addition, the authors aimed to subject these implant shells to an in vitro bacterial attachment assay with four bacterial pathogens (Staphylococcus epidermidis, S. aureus, Pseudomonas aeruginosa, and Ralstonia pickettii) and study the relationship among surface area, surface roughness, and bacterial growth. Results: Surface area measurement showed grouping of implants into high, intermediate, low, and minimal. Surface roughness showed a correlation with surface area. The in vitro assay showed a significant linear relationship between surface area and bacterial attachment/growth. The high surface area/roughness implant texture grew significantly more bacteria at 24 hours, whereas the minimal surface area/roughness implant textures grew significantly fewer bacteria of all types at 24 hours. For implants with intermediate and low surface areas, some species differences were observed, indicating possible affinity of specific bacterial species to surface morphology. Conclusions: Implant shells should be reclassified using surface area/roughness into four categories (high, intermediate, low, and minimal). This classification is superior to the use of descriptive terms such as macrotexture, microtexture, and nanotexture, which are not well correlated with objective measurement and/or functional outcomes.",
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The functional influence of breast implant outer shell morphology on bacterial attachment and growth. / Jones, Phoebe; Mempin, Maria; Hu, Honghua; Chowdhury, Durdana; Foley, Matthew; Cooter, Rodney; Adams, William P.; Vickery, Karen; Deva, Anand K.

In: Plastic and reconstructive surgery, Vol. 142, No. 4, 01.10.2018, p. 837-849.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - The functional influence of breast implant outer shell morphology on bacterial attachment and growth

AU - Jones,Phoebe

AU - Mempin,Maria

AU - Hu,Honghua

AU - Chowdhury,Durdana

AU - Foley,Matthew

AU - Cooter,Rodney

AU - Adams,William P.

AU - Vickery,Karen

AU - Deva,Anand K.

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Y1 - 2018/10/1

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