The generation of pharyngeal phase of swallow and its coordination with breathing

Interaction between the swallow and respiratory central pattern generators

Tara G. Bautista*, Qi Jian Sun, Paul M. Pilowsky

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingChapter

    25 Citations (Scopus)

    Abstract

    Swallowing and breathing utilize common muscles and an anatomical passage: the pharynx. The risk of aspiration of ingested material is minimized not only by the laryngeal adduction of the vocal folds and laryngeal elevation but also by the precise coordination of swallows with breathing. Namely, swallows: (1) are preferentially initiated in the postinspiratory/expiratory phase, (2) are accompanied by a brief apnea, and (3) are often followed by an expiration and delay of the next breath. This review summarizes the expiratory evidence on the brainstem regions comprising the central pattern generator (CPG) that produces the pharyngeal stage of swallow, how the motor acts of swallowing and breathing are coordinated, and lastly, brainstem regions where the swallowing and respiratory CPGs may interact in order to ensure "safe" swallows.

    Original languageEnglish
    Title of host publicationProgress in Brain Research
    EditorsGert Holstege, Caroline M. Beers , Hari H. Subramanian
    Place of PublicationAmsterdam, Netherlands
    PublisherElsevier
    Pages253-275
    Number of pages23
    Volume212
    ISBN (Print)9780444634887
    DOIs
    Publication statusPublished - 2014

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    Bautista, T. G., Sun, Q. J., & Pilowsky, P. M. (2014). The generation of pharyngeal phase of swallow and its coordination with breathing: Interaction between the swallow and respiratory central pattern generators. In G. Holstege, C. M. Beers , & H. H. Subramanian (Eds.), Progress in Brain Research (Vol. 212, pp. 253-275). Amsterdam, Netherlands: Elsevier. Progress in Brain Research https://doi.org/10.1016/B978-0-444-63488-7.00013-6