TY - GEN
T1 - The generation of post-inspiratory activity in laryngeal motoneurons
T2 - The 11th Oxford Conference on Modeling and Control of Breathing
AU - Bautista, Tara G.
AU - Burke, Peter G R
AU - Sun, Qi Jian
AU - Berkowitz, Robert G.
AU - Pilowsky, Paul M.
PY - 2010/1
Y1 - 2010/1
N2 - Breathing is a vegetative function that is altered during more complex behaviours such as exercise, vocalisation and respiratory protective reflexes. Recent years have seen recognition of the importance of respiratory pattern generation in addition to rhythm generation. Respiratory-modulated cranial motoneurons (laryngeal, pharyngeal, hypoglossal, facial) offer a unique insight into the control of respiration since: (1) they receive rhythmic respiratory inputs but; (2) their respiratory-modulated firing pattern differs to that of phrenic neurons to suit their function, (for example, hypoglossal motoneurons begin firing and thus the tongue depresses before the onset of phrenic nerve discharge and diaphragmatic during inspiration) and; (3) their activity is often altered in parallel with changes in respiration during stereotypical non-respiratory behaviours such as coughing, swallowing and sneeze. Here we review some mechanisms that modulate the respiratory-related activity of laryngeal motoneurons with an emphasis on the generation of post-inspiratory activity.
AB - Breathing is a vegetative function that is altered during more complex behaviours such as exercise, vocalisation and respiratory protective reflexes. Recent years have seen recognition of the importance of respiratory pattern generation in addition to rhythm generation. Respiratory-modulated cranial motoneurons (laryngeal, pharyngeal, hypoglossal, facial) offer a unique insight into the control of respiration since: (1) they receive rhythmic respiratory inputs but; (2) their respiratory-modulated firing pattern differs to that of phrenic neurons to suit their function, (for example, hypoglossal motoneurons begin firing and thus the tongue depresses before the onset of phrenic nerve discharge and diaphragmatic during inspiration) and; (3) their activity is often altered in parallel with changes in respiration during stereotypical non-respiratory behaviours such as coughing, swallowing and sneeze. Here we review some mechanisms that modulate the respiratory-related activity of laryngeal motoneurons with an emphasis on the generation of post-inspiratory activity.
UR - http://www.scopus.com/inward/record.url?scp=77952302509&partnerID=8YFLogxK
U2 - 10.1007/978-1-4419-5692-7_29
DO - 10.1007/978-1-4419-5692-7_29
M3 - Conference proceeding contribution
C2 - 20217338
AN - SCOPUS:77952302509
SN - 9781441956910
VL - 669
T3 - Advances in Experimental Medicine and Biology
SP - 143
EP - 149
BT - New Frontiers in Respiratory Control
A2 - Homma, Ikuo
A2 - Onimaru, Hiroshi
A2 - Fukuchi, Yoshinosuke
PB - Springer, Springer Nature
CY - New York
Y2 - 23 July 2009 through 26 July 2009
ER -