The genome of deep-sea vent chemolithoautotroph Thiomicrospira crunogena XCL-2

Kathleen M. Scott*, Stefan M. Sievert, Fereniki N. Abril, Lois A. Ball, Chantell J. Barrett, Rodrigo A. Blake, Amanda J. Boller, Patrick S G Chain, Justine A. Clark, Carisa R. Davis, Chris Detter, Kimberly F. Do, Kimberly P. Dobrinski, Brandon I. Faza, Kelly A. Fitzpatrick, Sharyn K. Freyermuth, Tara L. Harmer, Loren J. Hauser, Michael Hügler, Cheryl A. Kerfeld & 23 others Martin G. Klotz, William W. Kong, Miriam Land, Alla Lapidus, Frank W. Larimer, Dana L. Longo, Susan Lucas, Stephanie A. Malfatti, Steven E. Massey, Darlene D. Martin, Zoe McCuddin, Folker Meyer, Jessica L. Moore, Luis H. Ocampo, John H. Paul, Ian T. Paulsen, Douglas K. Reep, Qinghu Ren, Rachel L. Ross, Priscila Y. Sato, Phaedra Thomas, Lance E. Tinkham, Gary T. Zeruth

*Corresponding author for this work

Research output: Contribution to journalArticle

97 Citations (Scopus)

Abstract

Presented here is the complete genome sequence of Thiomicrospira crunogena XCL-2, representative of ubiquitous chemolithoautotrophic sulfur-oxidizing bacteria isolated from deep-sea hydrothermal vents. This gammaproteobacterium has a single chromosome (2,427,734 base pairs), and its genome illustrates many of the adaptations that have enabled it to thrive at vents globally. It has 14 methyl-accepting chemotaxis protein genes, including four that may assist in positioning it in the redoxcline. A relative abundance of coding sequences (CDSs) encoding regulatory proteins likely control the expression of genes encoding carboxysomes, multiple dissolved inorganic nitrogen and phosphate transporters, as well as a phosphonate operon, which provide this species with a variety of options for acquiring these substrates from the environment. Thiom. crunogena XCL-2 is unusual among obligate sulfur-oxidizing bacteria in relying on the Sox system for the oxidation of reduced sulfur compounds. The genome has characteristics consistent with an obligately chemolithoautotrophic lifestyle, including few transporters predicted to have organic allocrits, and Calvin-Benson-Bassham cycle CDSs scattered throughout the genome.

Original languageEnglish
Pages (from-to)2196-2212
Number of pages17
JournalPLoS Biology
Volume4
Issue number12
DOIs
Publication statusPublished - Nov 2006
Externally publishedYes

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    Scott, K. M., Sievert, S. M., Abril, F. N., Ball, L. A., Barrett, C. J., Blake, R. A., ... Zeruth, G. T. (2006). The genome of deep-sea vent chemolithoautotroph Thiomicrospira crunogena XCL-2. PLoS Biology, 4(12), 2196-2212. https://doi.org/10.1371/journal.pbio.0040383