Projects per year
Methods: A cluster randomised controlled trial (the Hide and Seek Project, HaSP) is underway to compare two different implementation approaches aimed at improving referral rates, and thus detection, of Lynch syndrome among colorectal cancer patients across eight Australian hospital networks. An in-depth process evaluation is being conducted alongside the trial and includes measures to collect comprehensive data on both implementation and intervention costs. These costs, in addition to HaSP outcome data, will be incorporated as inputs into an existing microsimulation model—Policy1-Lynch—to project the downstream economic and health impacts and determine the more cost-effective implementation approach from the Australian healthcare perspective.
Discussion: The ability to model the impact of different implementation approaches will enable the most efficient way of improving Lynch syndrome detection. The approach used in this study could also be applied to assess other implementation approaches aimed at increasing the uptake of cost-effective health interventions.
Trial registration: ANZCTR, ACTRN12618001072202. Registered on 27 June 2018.
Bibliographical noteCopyright © The Author(s) 2020. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.
Hide and seek with hereditary cancer: Improving detection of colorectal cancer patients with a high risk of Lynch syndrome
Taylor, N., Tucker, K., Macrae, F., Gill, A. J., Canfell, K., Pachter, N., Parkinson, B., Solomon, M., Shaw, T., Kench, J. G., Mitchell, G., Williams, R., Lakhani, S., Marfan, H., Debono, D., Long, J., Morris, S., Phan-Thien, K., Wright, C. M. & Potter, M.
30/06/17 → 30/06/21