Abstract
Apart from peculiarities of the cerebral circulation, required to perfuse the brain with the subject erect, the principles established for function of the human systemic circulation (pulsatile flow at input and steady flow at output in capillaries) are identical to those established for other mammals. Assumption of the erect posture first as Homo erectus, then as Homo sapiens, conferred huge advantage to humans and led to command of the mammalian kingdom. But this required a circulation which could perfuse the brain securely against gravity in all positions of the body. This review covers what presently is known about the human cerebral circulation, and how such knowledge can be applied in some clinical conditions including development of dementia in older subjects, and in management of patients with elevation of intra-cranial pressure in younger subjects.
Original language | English |
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Pages (from-to) | 197-211 |
Number of pages | 15 |
Journal | Artery Research |
Volume | 26 |
Issue number | 4 |
DOIs | |
Publication status | Published - Dec 2020 |
Bibliographical note
Copyright the Publisher 2020. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.Keywords
- Wave reflection
- reflection coefficient
- pressure waves
- flow waves
- intracranial pressure
- pulse wave analysis
- Wave reflection reflection coefficient pressure waves flow waves intracranial pressure pulse wave analysis