The impact of hippocampal damage on appetitive control

Andrea Zuniga, Richard J. Stevenson*, Zoe C. Thayer, Laurie A. Miller, Heather M. Francis, Supreet Saluja, Armin Nikpour

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)


    Animal data indicates the hippocampus assists appetite-regulation.  We tested this in humans, contrasting two patients (DW, JC) with hippocampal damage to controls on an appetite-regulation test conducted hungry and sated.  When hungry, controlsviewed palatable snacks and reported a desire to eat them, a memory-based judgment.  After sampling them, they reported liking their taste.  Post-lunch (DW ate little, precluding a test of our hypothesis), controls showed a large decrease in desire for the snacks, but less change in taste-liking.  JC ate like controls, but reported no change in desire across states, suggesting that the human hippocampus also contributes to appetite-regulation.

    Original languageEnglish
    Pages (from-to)305-312
    Number of pages8
    Issue number5
    Publication statusPublished - 2 Sept 2020


    • appetite
    • desire
    • eating
    • Hippocampus
    • inhibition
    • liking
    • wanting


    Dive into the research topics of 'The impact of hippocampal damage on appetitive control'. Together they form a unique fingerprint.

    Cite this