The impact of Primary Ciliary Dyskinesia on the upper respiratory tract

Lucy C. Morgan*, Catherine S. Birman

*Corresponding author for this work

    Research output: Contribution to journalReview article

    16 Citations (Scopus)

    Abstract

    Primary Ciliary Dyskinesia (PCD) is an autosomal recessive genetic condition affecting the function of motile cilia. The upper respiratory tract is lined with ciliated epithelium and hence a hallmark of PCD is the development, from the neonatal period onwards, of persisting secretion retention and suppurative infection in the middle ear, nose and facial sinuses [1]. This review aims to remind the clinician involved in the care of a patient with PCD of the complexities of making the diagnosis of chronic rhinosinusitis (CRS) and chronic otitis media with effusion (ChOME), the morbidity associated with CRS and ChOME and of current evidence of best practice for the management of these conditions.

    Original languageEnglish
    Pages (from-to)33-38
    Number of pages6
    JournalPaediatric Respiratory Reviews
    Volume18
    DOIs
    Publication statusPublished - 1 Mar 2016

    Keywords

    • Chronic otitis media with effusion
    • Chronic rhinosinusitis
    • Primary ciliary dyskinesia

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