The importance of brain banks for molecular neuropathological research: the New South Wales Tissue Resource Centre experience

Irina Dedova; Antony Harding; Donna Sheedy; Therese Garrick; Nina Sundqvist; Clare Hunt; Juliette Gillies; Clive G. Harper

doi:10.3390/ijms10010366

The importance of brain banks for molecular neuropathological research: the New South Wales Tissue Resource Centre experience

Irina Dedova^*, Antony Harding, Donna Sheedy, Therese Garrick, Nina Sundqvist, Clare Hunt, Juliette Gillies, Clive G. Harper

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

30 Citations (Scopus)

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Abstract

New developments in molecular neuropathology have evoked increased demands for postmortem human brain tissue. The New South Wales Tissue Resource Centre (TRC) at The University of Sydney has grown from a small tissue collection into one of the leading international brain banking facilities, which operates with best practice and quality control protocols. The focus of this tissue collection is on schizophrenia and allied disorders, alcohol use disorders and controls. This review highlights changes in TRC operational procedures dictated by modern neuroscience, and provides examples of applications of modern molecular techniques to study the neuropathogenesis of many different brain disorders.

Original language	English
Pages (from-to)	366-384
Number of pages	19
Journal	International Journal of Molecular Sciences
Volume	10
Issue number	1
DOIs	https://doi.org/10.3390/ijms10010366
Publication status	Published - Jan 2009
Externally published	Yes

Bibliographical note

Copyright the Author(s) 2009. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

Alcohol
Brain bank
Clinical characterization
Genome
Human
Molecular neuropathology
Postmortem
Proteome
Receptor binding
Schizophrenia

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10.3390/ijms10010366

Publsiher version (open access)Final published version, 140 KBLicence: CC BY

Cite this

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The importance of brain banks for molecular neuropathological research: the New South Wales Tissue Resource Centre experience

Abstract

Bibliographical note

Keywords

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