TY - JOUR
T1 - The International Society of Urological Pathology (ISUP) Vancouver classification of renal neoplasia
AU - Srigley, John R.
AU - Delahunt, Brett
AU - Eble, John N.
AU - Egevad, Lars
AU - Epstein, Jonathan I.
AU - Grignon, David
AU - Hes, Ondrej
AU - Moch, Holger
AU - Montironi, Rodolfo
AU - Tickoo, Satish K.
AU - Zhou, Ming
AU - Argani, Pedram
AU - Abraham, Anila
AU - Adeniran, Adebowale
AU - Ahmed, Khalid
AU - Al Ahmadie, Hikmat
AU - Algaba, Ferran
AU - Allan, Robert
AU - Amin, Mahul
AU - Axcrona, Ulrika
AU - Barry, Marc
AU - Baydar, Dilek
AU - Bégin, Louis
AU - Berney, Dan
AU - Bethwaite, Peter
AU - Billis, Athanase
AU - Birbe, Ruth
AU - Bonsib, Stephen
AU - Bostwick, David
AU - Brimo, Fadi
AU - Cathro, Helen
AU - Chen, Ying Bei
AU - Cheng, Liang
AU - Cheville, John
AU - Cho, Yong Mee
AU - Chuang, Ai Ying
AU - Cohen, Cynthia
AU - Crist, Henry
AU - Delprado, Warick
AU - Deng, Fang Ming
AU - Evans, Andrew
AU - Fadare, Oluwole
AU - Fajardo, Daniel
AU - Falzarano, Sara
AU - Fine, Samson
AU - Fleming, Stewart
AU - Fridman, Eddie
AU - Furusato, Bungo
AU - Ganji, Masoud
AU - Ghayouri, Masoumeh
AU - Giannico, Giovanna
AU - Gokden, Neriman
AU - Griffiths, David
AU - Gupta, Nilesh
AU - Hameed, Omar
AU - Hirsch, Michelle
AU - Huang, Jiaoti
AU - Huang, Wei
AU - Van De Kaa, Christina Hulsbergen
AU - Humphrey, Peter
AU - Hussein, Sundus
AU - Iczkowski, Kenneth
AU - Jimenez, Rafael
AU - Jones, Edward
AU - Jufe, Laura Irene
AU - Kench, James
AU - Kida, Masatoshi
AU - Kristiansen, Glen
AU - Kunju, Lakshmi Priya
AU - Lane, Zhaoli
AU - Latour, Mathieu
AU - Lewin, Claudio
AU - Lie, Kathrine
AU - Lloreta, Josep
AU - Loftus, Barbara
AU - Lopez-Beltran, Antonio
AU - Maclean, Fiona
AU - Magi-Galluzzi, Cristina
AU - Martignoni, Guido
AU - McHale, Teresa
AU - McKenney, Jesse
AU - Merino, Maria
AU - Miller, Rose
AU - Miyamoto, Hiroshi
AU - Murphy, Hedwig
AU - Nacey, John
AU - Nazeer, Tipu
AU - Nesi, Gabriella
AU - Netto, George
AU - Nichols, Peter
AU - O'Donnell, Marie
AU - Olgac, Semra
AU - Orozco, Roberto
AU - Osunkoya, Adeboye
AU - Ozagari, Aysim
AU - Pan, Chin Chen
AU - Parwani, Anil
AU - Perry-Keene, Joanna
AU - Petraki, Constantina
AU - Picken, Maria
AU - Pyda-Karwicka, Maria
AU - Reuter, Victor
AU - Rezaei, Katayoon
AU - Rioux-Leclercq, Nathalie
AU - Robinson, Brian
AU - Rohan, Stephen
AU - Ronchetti, Ruben
AU - Russell, Laurie
AU - Samaratunga, Hemamali
AU - Scarpelli, Marina
AU - Shabaik, Ahmed
AU - Shah, Rajal
AU - Shanks, Jonathan
AU - Shen, Steven
AU - Shevchuk, Maria
AU - Sibony, Mathilde
AU - Srinivasan, Bhuvana
AU - Susani, Martin
AU - Suzigan, Sueli
AU - Sweet, Joan
AU - Takahashi, Hiroyuki
AU - Tamboli, Pheroze
AU - Tan, Puay Hoon
AU - Trias, Isabel
AU - Trpkov, Kiril
AU - True, Larry
AU - Tsuzuki, Toyonori
AU - Vakar-Lopez, Funda
AU - Van Der Kwast, Theo
AU - Wang, Cheng
AU - Warren, Anne
AU - Yao, Jorge
AU - Yilmaz, Asli
AU - Zhao, Jin
AU - Zynger, Debra
AU - The ISUP Renal Tumor Panel
PY - 2013
Y1 - 2013
N2 - The classification working group of the International Society of Urological Pathology consensus conference on renal neoplasia was in charge of making recommendations regarding additions and changes to the current World Health Organization Classification of Renal Tumors (2004). Members of the group performed an exhaustive literature review, assessed the results of the preconference survey and participated in the consensus conference discussion and polling activities. On the basis of the above inputs, there was consensus that 5 entities should be recognized as new distinct epithelial tumors within the classification system: tubulocystic renal cell carcinoma (RCC), acquired cystic disease-associated RCC, clear cell (tubulo) papillary RCC, the MiT family translocation RCCs (in particular t(6;11) RCC), and hereditary leiomyomatosis RCC syndrome-associated RCC. In addition, there are 3 rare carcinomas that were considered as emerging or provisional new entities: thyroid-like follicular RCC; succinate dehydrogenase B deficiency-associated RCC; and ALK translocation RCC. Further reports of these entities are required to better understand the nature and behavior of these highly unusual tumors. There were a number of new concepts and suggested modifications to the existing World Health Organization 2004 categories. Within the clear cell RCC group, it was agreed upon that multicystic clear cell RCC is best considered as a neoplasm of low malignant potential. There was agreement that subtyping of papillary RCC is of value and that the oncocytic variant of papillary RCC should not be considered as a distinct entity. The hybrid oncocytic chromophobe tumor, which is an indolent tumor that occurs in 3 settings, namely Birt-Hogg-Dubé Syndrome, renal oncocytosis, and as a sporadic neoplasm, was placed, for the time being, within the chromophobe RCC category. Recent advances related to collecting duct carcinoma, renal medullary carcinoma, and mucinous spindle cell and tubular RCC were elucidated. Outside of the epithelial category, advances in our understanding of angiomyolipoma, including the epithelioid and epithelial cystic variants, were considered. In addition, the apparent relationship between cystic nephroma and mixed epithelial and stromal tumor was discussed, with the consensus that these tumors form a spectrum of neoplasia. Finally, it was thought that the synovial sarcoma should be removed from the mixed epithelial and mesenchymal category and placed within the sarcoma group. The new classification is to be referred to as the International Society of Urological Pathology Vancouver Classification of Renal Neoplasia.
AB - The classification working group of the International Society of Urological Pathology consensus conference on renal neoplasia was in charge of making recommendations regarding additions and changes to the current World Health Organization Classification of Renal Tumors (2004). Members of the group performed an exhaustive literature review, assessed the results of the preconference survey and participated in the consensus conference discussion and polling activities. On the basis of the above inputs, there was consensus that 5 entities should be recognized as new distinct epithelial tumors within the classification system: tubulocystic renal cell carcinoma (RCC), acquired cystic disease-associated RCC, clear cell (tubulo) papillary RCC, the MiT family translocation RCCs (in particular t(6;11) RCC), and hereditary leiomyomatosis RCC syndrome-associated RCC. In addition, there are 3 rare carcinomas that were considered as emerging or provisional new entities: thyroid-like follicular RCC; succinate dehydrogenase B deficiency-associated RCC; and ALK translocation RCC. Further reports of these entities are required to better understand the nature and behavior of these highly unusual tumors. There were a number of new concepts and suggested modifications to the existing World Health Organization 2004 categories. Within the clear cell RCC group, it was agreed upon that multicystic clear cell RCC is best considered as a neoplasm of low malignant potential. There was agreement that subtyping of papillary RCC is of value and that the oncocytic variant of papillary RCC should not be considered as a distinct entity. The hybrid oncocytic chromophobe tumor, which is an indolent tumor that occurs in 3 settings, namely Birt-Hogg-Dubé Syndrome, renal oncocytosis, and as a sporadic neoplasm, was placed, for the time being, within the chromophobe RCC category. Recent advances related to collecting duct carcinoma, renal medullary carcinoma, and mucinous spindle cell and tubular RCC were elucidated. Outside of the epithelial category, advances in our understanding of angiomyolipoma, including the epithelioid and epithelial cystic variants, were considered. In addition, the apparent relationship between cystic nephroma and mixed epithelial and stromal tumor was discussed, with the consensus that these tumors form a spectrum of neoplasia. Finally, it was thought that the synovial sarcoma should be removed from the mixed epithelial and mesenchymal category and placed within the sarcoma group. The new classification is to be referred to as the International Society of Urological Pathology Vancouver Classification of Renal Neoplasia.
KW - Classification
KW - Diagnosis
KW - International Society of Urological Pathology
KW - Morphology
KW - Renal cell carcinoma
KW - Renal neoplasia
UR - http://www.scopus.com/inward/record.url?scp=84900390656&partnerID=8YFLogxK
U2 - 10.1097/PAS.0b013e318299f2d1
DO - 10.1097/PAS.0b013e318299f2d1
M3 - Article
C2 - 24025519
AN - SCOPUS:84900390656
SN - 0147-5185
VL - 37
SP - 1469
EP - 1489
JO - American Journal of Surgical Pathology
JF - American Journal of Surgical Pathology
IS - 10
ER -