卫生技术成本-效果阈值测算方法、应用进展及启示

Cost effectiveness threshold is an important basis to support the pricing negotiation and reimbursement decision for drugs and medical devices.Setting an appropriate cost effectiveness threshold is a major part of HTA development in China.In the current HTA practice,however,an evidence-based cost effectiveness threshold is still lacking and thus becomes a pressing research priority.It looks into the international progress on methodologies and applications of cost effectiveness threshold.Based on the current status in China,it proposes suggestions for future research directions,including establishing the national cost effectiveness threshold,taking into account equity and ethical considerations,heterogeneity in regions and diseases,as well as examining alternative methods and identifying the one most suitable for China.