The Milan System for Reporting Salivary Gland Cytopathology

proposed modifications to improve clinical utility

Francesco Mazzola*, Ruta Gupta, Peter P. Luk, Carsten Palme, Jonathan R. Clark, Tsu Hui (Hubert) Low

*Corresponding author for this work

Research output: Contribution to journalArticle

4 Citations (Scopus)


Background: Fine-needle aspiration of a salivary gland lesion is a well-established diagnostic procedure that aids management decisions. Recently, the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) classification has been proposed in order to improve the reproducibility and communication in the management of salivary gland lesions. Methods: A total of 375 patient's cytological reports collected between January 2010 and December 2017 were reviewed and reclassified according to MSRSGC and a risk of malignancy was calculated for each of the category. Results: The rate of malignancy in MSRSGC classification was 19.0%, 11.8%, 25.0%, 5.5%, 50.0%, 71.4%, and 94.6% for each of the category (I, II, III, IVa, IVb, V, and VI), respectively. Conclusion: The MSRSGC classification is a valuable tool in everyday practice. The modified version of MSRSGC aims to improve the surgical relevance and facilitate uniform management.

Original languageEnglish
Pages (from-to)2566-2573
Number of pages8
JournalHead and Neck
Issue number8
Publication statusPublished - 1 Aug 2019
Externally publishedYes


  • cytology
  • fine-needle aspiration
  • head and neck tumors
  • Milan classification
  • salivary gland

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