The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data

Yan Liu*, Ryan McBride, Mark Stoll, Angelina S. Palma, Lisete Silva, Sanjay Agravat, Kiyoko F. Aoki-Kinoshita, Matthew P. Campbell, Catherine E. Costello, Anne Dell, Stuart M. Haslam, Niclas G. Karlsson, Kay Hooi Khoo, Daniel Kolarich, Milos V. Novotny, Nicolle H. Packer, Rene Ranzinger, Erdmann Rapp, Pauline M. Rudd, Weston B. StruweMichael Tiemeyer, Lance Wells, William S. York, Joseph Zaia, Carsten Kettner, James C. Paulson, Ten Feizi, David F. Smith

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    76 Citations (Scopus)
    34 Downloads (Pure)

    Abstract

    MIRAGE (Minimum Information Required for A Glycomics Experiment) is an initiative that was created by experts in the fields of glycobiology, glycoanalytics and glycoinformatics to produce guidelines for reporting results from the diverse types of experiments and analyses used in structural and functional studies of glycans in the scientific literature. As a sequel to the guidelines for sample preparation (Struwe et al. 2016, Glycobiology, 26:907-910) and mass spectrometry data (Kolarich et al. 2013, Mol. Cell Proteomics, 12:991-995), here we present the first version of guidelines intended to improve the standards for reporting data from glycan microarray analyses. For each of eight areas in the workflow of a glycan microarray experiment, we provide guidelines for the minimal information that should be provided in reporting results. We hope that the MIRAGE glycan microarray guidelines proposed here will gain broad acceptance by the community, and will facilitate interpretation and reproducibility of the glycan microarray results with implications in comparison of data from different laboratories and eventual deposition of glycan microarray data in international databases.

    Original languageEnglish
    Pages (from-to)280-284
    Number of pages5
    JournalGlycobiology
    Volume27
    Issue number4
    DOIs
    Publication statusPublished - Apr 2017

    Bibliographical note

    Copyright the Author(s) 2017. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

    Keywords

    • glycan microarrays
    • glycans
    • glycobiology
    • glycomics
    • MIRAGE

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