The Osseointegration Group of Australia Accelerated Protocol (OGAAP-1) for two-stage osseointegrated reconstruction of amputated limbs

M. Al Muderis, K. Tetsworth, A. Khemka, S. J. Lord, S. Wilmot, B. Bosley, V. Glatt*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    48 Citations (Scopus)


    AIMS: This study describes the Osseointegration Group of Australia's Accelerated Protocol two-stage strategy (OGAAP-1) for the osseointegrated reconstruction of amputated limbs.

    PATIENTS AND METHODS: We report clinical outcomes in 50 unilateral trans-femoral amputees with a mean age of 49.4 years (24 to 73), with a minimum one-year follow-up. Outcome measures included the Questionnaire for persons with a Trans-Femoral Amputation, the health assessment questionnaire Short-Form-36 Health Survey, the Amputation Mobility Predictor scores presented as K-levels, 6 Minute Walk Test and timed up and go tests. Adverse events included soft-tissue problems, infection, fractures and failure of the implant.

    RESULTS: Our results demonstrated statistically significant improvements in all five outcome measures. A total of 27 patients experienced adverse events but at the conclusion of the study, all 50 were walking on osseointegrated prostheses.

    CONCLUSION: These results demonstrate that osseointegrated prostheses are a suitable alternative to socket-fit devices for amputees experiencing socket-related discomfort and that our strategy offers more rapid progress to walking than other similar protocols.

    Original languageEnglish
    Pages (from-to)952-960
    Number of pages9
    JournalBone and Joint Journal
    Issue number7
    Publication statusPublished - 1 Jul 2016


    • bone-anchored prosthesis
    • lower limb amputation
    • lower limb reconstructive surgery
    • osseointegration
    • prosthetics
    • rehabilitation

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