TY - JOUR
T1 - The relationship between acute mastoiditis and antibiotic use for acute otitis media in children
AU - Ho, David
AU - Rotenberg, Brian W.
AU - Berkowitz, Robert G.
PY - 2008/1
Y1 - 2008/1
N2 - Objective: To determine the relationship between prior antibiotic use and the development of acute mastoiditis (AM) in children. Design: Retrospective review. Setting: Tertiary pediatric center. Patients: We identified 129 patients with AM who were admitted to our center between 1996 and 2005. Main Outcome Measure: Proportion of children who developed AM. Results: A total of only 67 patients (51.9%) had undergone any antimicrobial treatment prior to hospital admission. In 1996, 64% of patients with AM had received antibiotics for acute otitis media (AOM) prior to admission (n=7 of 11), but this percentage had steadily decreased to 27% by 2005 (n=4 of 15). The yearly number of cases of AM treated in our institution has remained stable over this period. A subperiosteal abscess was identified in 45 patients (34.9%), while the remainder (n=84) had postauricular inflammation only (65.1%). Nineteen patients with a subperiosteal abscess (42%) and 48 patients without a subperiosteal abscess (57%) had undergone prehospitalization antimicrobial therapy for suppurative AOM. There was no significant difference in antibiotic use between the numbers of patients with or without a subperiosteal abscess. Regarding the sensitivity of bacteria isolated from patients with a subperiosteal abscess, only 1 patient was infected with an organism that was not sensitive to the prehospitalization antibiotic prescribed. Conclusion: Use of antibiotics to treat suppurative AOM in children might not influence the subsequent development of AM.
AB - Objective: To determine the relationship between prior antibiotic use and the development of acute mastoiditis (AM) in children. Design: Retrospective review. Setting: Tertiary pediatric center. Patients: We identified 129 patients with AM who were admitted to our center between 1996 and 2005. Main Outcome Measure: Proportion of children who developed AM. Results: A total of only 67 patients (51.9%) had undergone any antimicrobial treatment prior to hospital admission. In 1996, 64% of patients with AM had received antibiotics for acute otitis media (AOM) prior to admission (n=7 of 11), but this percentage had steadily decreased to 27% by 2005 (n=4 of 15). The yearly number of cases of AM treated in our institution has remained stable over this period. A subperiosteal abscess was identified in 45 patients (34.9%), while the remainder (n=84) had postauricular inflammation only (65.1%). Nineteen patients with a subperiosteal abscess (42%) and 48 patients without a subperiosteal abscess (57%) had undergone prehospitalization antimicrobial therapy for suppurative AOM. There was no significant difference in antibiotic use between the numbers of patients with or without a subperiosteal abscess. Regarding the sensitivity of bacteria isolated from patients with a subperiosteal abscess, only 1 patient was infected with an organism that was not sensitive to the prehospitalization antibiotic prescribed. Conclusion: Use of antibiotics to treat suppurative AOM in children might not influence the subsequent development of AM.
UR - http://www.scopus.com/inward/record.url?scp=38549122512&partnerID=8YFLogxK
U2 - 10.1001/archotol.134.1.45
DO - 10.1001/archotol.134.1.45
M3 - Article
C2 - 18209135
AN - SCOPUS:38549122512
VL - 134
SP - 45
EP - 48
JO - Archives of Otolaryngology - Head and Neck Surgery
JF - Archives of Otolaryngology - Head and Neck Surgery
SN - 0886-4470
IS - 1
ER -