The thalamus as a relay station and gatekeeper: relevance to brain disorders

Ahmed A. Moustafa*, Ryan D. McMullan, Bjorn Rostron, Doaa H. Hewedi, Harry H. Haladjian

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


Here, we provide a review of behavioural, cognitive, and neural studies of the thalamus, including its role in attention, consciousness, sleep, and motor processes. We further discuss neuropsychological and brain disorders associated with thalamus function, including Parkinson's disease, Alzheimer's disease, Korsakoff's syndrome, and sleep disorders. Importantly, we highlight how thalamus-related processes and disorders can be explained by the role of the thalamus as a relay station.

Original languageEnglish
Pages (from-to)203-218
Number of pages16
JournalReviews in the Neurosciences
Issue number2
Publication statusPublished - 1 Feb 2017
Externally publishedYes


  • Alzheimer's disease
  • consciousness
  • hemiballismus
  • Korsakoff's syndrome
  • Parkinson's disease
  • relay station
  • sleep
  • thalamus
  • Tourette syndrome


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