Theories of etiopathogenesis of breast implant-associated anaplastic large cell lymphoma

Pratik Rastogi, Edward Riordan, David Moon, Anand K. Deva

Research output: Contribution to journalReview articlepeer-review

25 Citations (Scopus)

Abstract

Breast implant-associated anaplastic large cell lymphoma is a malignancy of T lymphocytes that is associated with the use of textured breast implants in both esthetic and reconstructive surgeries. Patients typically present with a delayed seroma 8-10 years following implantation or-less commonly-with a capsular mass or systemic disease. Current theories on disease pathogenesis focus on the interplay among textured implants, Gram-negative bacteria, host genetics, and time. The possible roles of silicone leachables and particles have been less well substantiated. This review aims to synthesize the existing scientific evidence regarding breast implant-associated anaplastic large cell lymphoma etiopathogenesis.

Original languageEnglish
Pages (from-to)23S-29S
Number of pages7
JournalPlastic and Reconstructive Surgery
Volume143
Issue number3
DOIs
Publication statusPublished - 1 Mar 2019

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