Therapeutic approaches in trauma-induced coagulopathy

M. Spivey, M. J. A. Parr*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

42 Citations (Scopus)


Coagulopathy is a phenomenon which is a life threatening complication in the trauma patient who has sustained significant injuries and blood loss. With our increasing understanding of the mechanisms which drive the coagulopathy and the availability of new treatment options, most notably recombinant factor VIIa (rFVIIa), we are now able to treat those patients who have had a massive traumatic haemorrhage with greater efficacy. This paper reviews the current considerations in dealing with patients with trauma-induced coagulopathy and offers a strategy for their management.

Original languageEnglish
Pages (from-to)281-289
Number of pages9
JournalMinerva Anestesiologica
Issue number6
Publication statusPublished - 1 Jun 2005
Externally publishedYes


  • Blood transfusion
  • Consumptive coagulopathy
  • Critical care
  • Trauma


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