THERE ARE FEW CATECHOLAMINE‐ OR NEUROPEPTIDE Y‐CONTAINING SYNAPSES IN THE INTERMEDIOLATERAL CELL COLUMN OF RAT THORACIC SPINAL CORD

Ida J. Llewellyn‐Smith; Jane B. Minson; Paul M. Pilowsky; John P. Chalmers

doi:10.1111/j.1440-1681.1991.tb01418.x

THERE ARE FEW CATECHOLAMINE‐ OR NEUROPEPTIDE Y‐CONTAINING SYNAPSES IN THE INTERMEDIOLATERAL CELL COLUMN OF RAT THORACIC SPINAL CORD

Ida J. Llewellyn‐Smith^*, Jane B. Minson, Paul M. Pilowsky, John P. Chalmers

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

1. A quantitative electron microscopic immunocytochemical technique was used to assess the number of synapses immunoreactive for tyrosine hydroxylase (TH), phenylethanolamine N‐methyltransferase (PNMT) and neuropeptide Y (NPY) in the intermediolateral cell column in segments T2 and T3 of rat thoracic spinal cord. 2. TH synapses comprised about 5%; PNMT synapses 1–2%; and NPY synapses 1–2% of the total number of synapses in the intermediolateral cell column. All three types of synapses were predominantly or exclusively on dendrites. 3. Our results suggest that catecholamine/NPY neurons may not provide a major synaptic input to sympathetic preganglionic neurons in rat upper thoracic spinal cord.

Original language	English
Pages (from-to)	111-115
Number of pages	5
Journal	Clinical and Experimental Pharmacology and Physiology
Volume	18
Issue number	2
DOIs	https://doi.org/10.1111/j.1440-1681.1991.tb01418.x
Publication status	Published - 1991

Keywords

immunocytochemistry
neuropeptide Y
phenylethanolamine N‐methyltransferase
sympathetic preganglionic neurons
tyrosine hydroxylase
ultrastructure.

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10.1111/j.1440-1681.1991.tb01418.x

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abstract = "1. A quantitative electron microscopic immunocytochemical technique was used to assess the number of synapses immunoreactive for tyrosine hydroxylase (TH), phenylethanolamine N‐methyltransferase (PNMT) and neuropeptide Y (NPY) in the intermediolateral cell column in segments T2 and T3 of rat thoracic spinal cord. 2. TH synapses comprised about 5%; PNMT synapses 1–2%; and NPY synapses 1–2% of the total number of synapses in the intermediolateral cell column. All three types of synapses were predominantly or exclusively on dendrites. 3. Our results suggest that catecholamine/NPY neurons may not provide a major synaptic input to sympathetic preganglionic neurons in rat upper thoracic spinal cord.",

keywords = "immunocytochemistry, neuropeptide Y, phenylethanolamine N‐methyltransferase, sympathetic preganglionic neurons, tyrosine hydroxylase, ultrastructure.",

author = "Llewellyn‐Smith, {Ida J.} and Minson, {Jane B.} and Pilowsky, {Paul M.} and Chalmers, {John P.}",

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doi = "10.1111/j.1440-1681.1991.tb01418.x",

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AU - Minson, Jane B.

AU - Pilowsky, Paul M.

AU - Chalmers, John P.

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KW - neuropeptide Y

KW - phenylethanolamine N‐methyltransferase

KW - sympathetic preganglionic neurons

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KW - ultrastructure.

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THERE ARE FEW CATECHOLAMINE‐ OR NEUROPEPTIDE Y‐CONTAINING SYNAPSES IN THE INTERMEDIOLATERAL CELL COLUMN OF RAT THORACIC SPINAL CORD

Abstract

Keywords

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