Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors

Yu Yu; Danuta S. Kalinowski; Zaklina Kovacevic; Aritee R. Siafakas; Patric J. Jansson; Christian Stefani; David B. Lovejoy; Philip C. Sharpe; Paul V. Bernhardt; Des R. Richardson

doi:10.1021/jm900552r

Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors

Yu Yu, Danuta S. Kalinowski, Zaklina Kovacevic, Aritee R. Siafakas, Patric J. Jansson, Christian Stefani, David B. Lovejoy, Philip C. Sharpe, Paul V. Bernhardt, Des R. Richardson^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

376 Citations (Scopus)

Original language	English
Pages (from-to)	5271-5294
Number of pages	24
Journal	Journal of Medicinal Chemistry
Volume	52
Issue number	17
DOIs	https://doi.org/10.1021/jm900552r
Publication status	Published - 10 Sept 2009
Externally published	Yes

Keywords

PYRIDOXAL ISONICOTINOYL HYDRAZONE
EFFECTIVE ANTIPROLIFERATIVE AGENTS
METASTASIS SUPPRESSOR GENE
ALPHA-(N)-HETEROCYCLIC CARBOXALDEHYDE THIOSEMICARBAZONES
DIVALENT METAL TRANSPORTER-1
SELECTIVE ANTITUMOR-ACTIVITY
INTRACELLULAR LABILE IRON
CELL-CYCLE PROGRESSION
ANTI-MALARIAL AGENTS
BREAST-CANCER CELLS

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@article{0b5f4f624efa4147ae45f9539aef97ee,

title = "Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors",

keywords = "PYRIDOXAL ISONICOTINOYL HYDRAZONE, EFFECTIVE ANTIPROLIFERATIVE AGENTS, METASTASIS SUPPRESSOR GENE, ALPHA-(N)-HETEROCYCLIC CARBOXALDEHYDE THIOSEMICARBAZONES, DIVALENT METAL TRANSPORTER-1, SELECTIVE ANTITUMOR-ACTIVITY, INTRACELLULAR LABILE IRON, CELL-CYCLE PROGRESSION, ANTI-MALARIAL AGENTS, BREAST-CANCER CELLS",

author = "Yu Yu and Kalinowski, \{Danuta S.\} and Zaklina Kovacevic and Siafakas, \{Aritee R.\} and Jansson, \{Patric J.\} and Christian Stefani and Lovejoy, \{David B.\} and Sharpe, \{Philip C.\} and Bernhardt, \{Paul V.\} and Richardson, \{Des R.\}",

year = "2009",

month = sep,

day = "10",

doi = "10.1021/jm900552r",

language = "English",

volume = "52",

pages = "5271--5294",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

number = "17",

}

TY - JOUR

T1 - Thiosemicarbazones from the old to new

T2 - iron chelators that are more than just ribonucleotide reductase inhibitors

AU - Yu, Yu

AU - Kalinowski, Danuta S.

AU - Kovacevic, Zaklina

AU - Siafakas, Aritee R.

AU - Jansson, Patric J.

AU - Stefani, Christian

AU - Lovejoy, David B.

AU - Sharpe, Philip C.

AU - Bernhardt, Paul V.

AU - Richardson, Des R.

PY - 2009/9/10

Y1 - 2009/9/10

KW - PYRIDOXAL ISONICOTINOYL HYDRAZONE

KW - EFFECTIVE ANTIPROLIFERATIVE AGENTS

KW - METASTASIS SUPPRESSOR GENE

KW - ALPHA-(N)-HETEROCYCLIC CARBOXALDEHYDE THIOSEMICARBAZONES

KW - DIVALENT METAL TRANSPORTER-1

KW - SELECTIVE ANTITUMOR-ACTIVITY

KW - INTRACELLULAR LABILE IRON

KW - CELL-CYCLE PROGRESSION

KW - ANTI-MALARIAL AGENTS

KW - BREAST-CANCER CELLS

UR - https://www.scopus.com/pages/publications/69949108747

U2 - 10.1021/jm900552r

DO - 10.1021/jm900552r

M3 - Article

C2 - 19601577

SN - 0022-2623

VL - 52

SP - 5271

EP - 5294

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 17

ER -

Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors

Keywords

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