Time gated fluorescent flow cytometer

Dayong Jin; Jim Piper; Russell Connally

Time gated fluorescent flow cytometer

Dayong Jin (Inventor), Jim Piper (Inventor), Russell Connally (Inventor)

Research output: Patent

Abstract

An apparatus (10) for detecting a particle (12) labelled with a fluorescent marker is disclosed. The apparatus (10) has a flow cell (16) being adapted to contain a fluid (14) in which the particle (12) is suspended. A light source (28) is operatively coupled to the flow cell (16) and arranged for emitting a stimulating light (28) which is effective in optically exciting the fluorescent marker (12) for emitting a fluorescent light (30). The apparatus (10) also includes a spatial filter (50) across an optical path between the particle (12) and a time gated detector (32) operatively coupled to the flow cell (16) for detecting the fluorescent light (30).

Original language	English
Patent number	WO2008019448
IPC	G01N 21/64 2006.1,G01N 15/14 2006.1
Priority date	18/08/06
Filing date	17/08/07
Publication status	Submitted - 21 Feb 2008

Bibliographical note

Designated States
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)

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title = "Time gated fluorescent flow cytometer",

abstract = "An apparatus (10) for detecting a particle (12) labelled with a fluorescent marker is disclosed. The apparatus (10) has a flow cell (16) being adapted to contain a fluid (14) in which the particle (12) is suspended. A light source (28) is operatively coupled to the flow cell (16) and arranged for emitting a stimulating light (28) which is effective in optically exciting the fluorescent marker (12) for emitting a fluorescent light (30). The apparatus (10) also includes a spatial filter (50) across an optical path between the particle (12) and a time gated detector (32) operatively coupled to the flow cell (16) for detecting the fluorescent light (30).",

author = "Dayong Jin and Jim Piper and Russell Connally",

note = "Designated States AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG); WO2008019448; G01N 21/64 2006.1,G01N 15/14 2006.1",

year = "2008",

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TY - PAT

T1 - Time gated fluorescent flow cytometer

AU - Jin, Dayong

AU - Piper, Jim

AU - Connally, Russell

N1 - Designated States AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)

PY - 2008/2/21

Y1 - 2008/2/21

N2 - An apparatus (10) for detecting a particle (12) labelled with a fluorescent marker is disclosed. The apparatus (10) has a flow cell (16) being adapted to contain a fluid (14) in which the particle (12) is suspended. A light source (28) is operatively coupled to the flow cell (16) and arranged for emitting a stimulating light (28) which is effective in optically exciting the fluorescent marker (12) for emitting a fluorescent light (30). The apparatus (10) also includes a spatial filter (50) across an optical path between the particle (12) and a time gated detector (32) operatively coupled to the flow cell (16) for detecting the fluorescent light (30).

AB - An apparatus (10) for detecting a particle (12) labelled with a fluorescent marker is disclosed. The apparatus (10) has a flow cell (16) being adapted to contain a fluid (14) in which the particle (12) is suspended. A light source (28) is operatively coupled to the flow cell (16) and arranged for emitting a stimulating light (28) which is effective in optically exciting the fluorescent marker (12) for emitting a fluorescent light (30). The apparatus (10) also includes a spatial filter (50) across an optical path between the particle (12) and a time gated detector (32) operatively coupled to the flow cell (16) for detecting the fluorescent light (30).

M3 - Patent

M1 - WO2008019448

Y2 - 2007/08/17

ER -

Time gated fluorescent flow cytometer

Abstract

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