Tools to study individual genes and proteins

Ulf Landegren; Johan Banér; Fredrik Dahl; Jenny Göransson; Mats Gullberg; Sigrun Gustafsdottir; Sara Henriksson; Mathias Howell; Jonas Jarvius; Malin Jarvius; Henrik Johansson; Masood Kamali; Chatarina Larsson; Karl Johan Leuchowius; Jonas Melin; Fredrik Nikolajeff; Mats Nilsson; Edith Schallmeiner; Ola Söderberg; Johan Stenberg

Tools to study individual genes and proteins

Ulf Landegren^*, Johan Banér, Fredrik Dahl, Jenny Göransson, Mats Gullberg, Sigrun Gustafsdottir, Sara Henriksson, Mathias Howell, Jonas Jarvius, Malin Jarvius, Henrik Johansson, Masood Kamali, Chatarina Larsson, Karl Johan Leuchowius, Jonas Melin, Fredrik Nikolajeff, Mats Nilsson, Edith Schallmeiner, Ola Söderberg, Johan Stenberg

^*Corresponding author for this work

Department of Physics and Astronomy

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution

Abstract

A family of molecular tools will be described that taken together allow complex biological samples to be interrogated for large sets of target nucleic acid or protein molecules, extending down to even individual molecules. We have used the probes for single-molecule detection and counting in microscopic preparations and in microfabricated fluidic channels.

Original language	English
Title of host publication	Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Transducer Research Foundation
Pages	1057-1059
Number of pages	3
Volume	1
ISBN (Print)	0974361119, 9780974361116
Publication status	Published - 2005
Event	9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States Duration: 9 Oct 2005 → 13 Oct 2005

Other

Other	9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
Country	United States
City	Boston, MA
Period	9/10/05 → 13/10/05

Keywords

DNA microarrays
High-throughput genomics
Microfluidics
Molecular diagnostics
Molecular tools
Padlock probes
Proximity ligation
Rolling-circle amplification
Single-molecule detection

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Landegren, U., Banér, J., Dahl, F., Göransson, J., Gullberg, M., Gustafsdottir, S., ... Stenberg, J. (2005). Tools to study individual genes and proteins. In Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (Vol. 1, pp. 1057-1059). Transducer Research Foundation.

Landegren, Ulf ; Banér, Johan ; Dahl, Fredrik ; Göransson, Jenny ; Gullberg, Mats ; Gustafsdottir, Sigrun ; Henriksson, Sara ; Howell, Mathias ; Jarvius, Jonas ; Jarvius, Malin ; Johansson, Henrik ; Kamali, Masood ; Larsson, Chatarina ; Leuchowius, Karl Johan ; Melin, Jonas ; Nikolajeff, Fredrik ; Nilsson, Mats ; Schallmeiner, Edith ; Söderberg, Ola ; Stenberg, Johan. / Tools to study individual genes and proteins. Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Vol. 1 Transducer Research Foundation, 2005. pp. 1057-1059

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title = "Tools to study individual genes and proteins",

abstract = "A family of molecular tools will be described that taken together allow complex biological samples to be interrogated for large sets of target nucleic acid or protein molecules, extending down to even individual molecules. We have used the probes for single-molecule detection and counting in microscopic preparations and in microfabricated fluidic channels.",

keywords = "DNA microarrays, High-throughput genomics, Microfluidics, Molecular diagnostics, Molecular tools, Padlock probes, Proximity ligation, Rolling-circle amplification, Single-molecule detection",

author = "Ulf Landegren and Johan Ban{\'e}r and Fredrik Dahl and Jenny G{\"o}ransson and Mats Gullberg and Sigrun Gustafsdottir and Sara Henriksson and Mathias Howell and Jonas Jarvius and Malin Jarvius and Henrik Johansson and Masood Kamali and Chatarina Larsson and Leuchowius, {Karl Johan} and Jonas Melin and Fredrik Nikolajeff and Mats Nilsson and Edith Schallmeiner and Ola S{\"o}derberg and Johan Stenberg",

year = "2005",

language = "English",

isbn = "0974361119",

volume = "1",

pages = "1057--1059",

booktitle = "Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Transducer Research Foundation",

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Landegren, U, Banér, J, Dahl, F, Göransson, J, Gullberg, M, Gustafsdottir, S, Henriksson, S, Howell, M, Jarvius, J, Jarvius, M, Johansson, H, Kamali, M, Larsson, C, Leuchowius, KJ, Melin, J, Nikolajeff, F, Nilsson, M, Schallmeiner, E, Söderberg, O & Stenberg, J 2005, Tools to study individual genes and proteins. in Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. vol. 1, Transducer Research Foundation, pp. 1057-1059, 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005, Boston, MA, United States, 9/10/05.

Tools to study individual genes and proteins. / Landegren, Ulf; Banér, Johan; Dahl, Fredrik; Göransson, Jenny; Gullberg, Mats; Gustafsdottir, Sigrun; Henriksson, Sara; Howell, Mathias; Jarvius, Jonas; Jarvius, Malin; Johansson, Henrik; Kamali, Masood; Larsson, Chatarina; Leuchowius, Karl Johan; Melin, Jonas; Nikolajeff, Fredrik; Nilsson, Mats; Schallmeiner, Edith; Söderberg, Ola; Stenberg, Johan.

Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Vol. 1 Transducer Research Foundation, 2005. p. 1057-1059.

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution

TY - GEN

T1 - Tools to study individual genes and proteins

AU - Landegren, Ulf

AU - Banér, Johan

AU - Dahl, Fredrik

AU - Göransson, Jenny

AU - Gullberg, Mats

AU - Gustafsdottir, Sigrun

AU - Henriksson, Sara

AU - Howell, Mathias

AU - Jarvius, Jonas

AU - Jarvius, Malin

AU - Johansson, Henrik

AU - Kamali, Masood

AU - Larsson, Chatarina

AU - Leuchowius, Karl Johan

AU - Melin, Jonas

AU - Nikolajeff, Fredrik

AU - Nilsson, Mats

AU - Schallmeiner, Edith

AU - Söderberg, Ola

AU - Stenberg, Johan

PY - 2005

Y1 - 2005

N2 - A family of molecular tools will be described that taken together allow complex biological samples to be interrogated for large sets of target nucleic acid or protein molecules, extending down to even individual molecules. We have used the probes for single-molecule detection and counting in microscopic preparations and in microfabricated fluidic channels.

AB - A family of molecular tools will be described that taken together allow complex biological samples to be interrogated for large sets of target nucleic acid or protein molecules, extending down to even individual molecules. We have used the probes for single-molecule detection and counting in microscopic preparations and in microfabricated fluidic channels.

KW - DNA microarrays

KW - High-throughput genomics

KW - Microfluidics

KW - Molecular diagnostics

KW - Molecular tools

KW - Padlock probes

KW - Proximity ligation

KW - Rolling-circle amplification

KW - Single-molecule detection

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M3 - Conference proceeding contribution

SN - 0974361119

SN - 9780974361116

VL - 1

SP - 1057

EP - 1059

BT - Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Transducer Research Foundation

ER -