Tools to study individual genes and proteins

Ulf Landegren*, Johan Banér, Fredrik Dahl, Jenny Göransson, Mats Gullberg, Sigrun Gustafsdottir, Sara Henriksson, Mathias Howell, Jonas Jarvius, Malin Jarvius, Henrik Johansson, Masood Kamali, Chatarina Larsson, Karl Johan Leuchowius, Jonas Melin, Fredrik Nikolajeff, Mats Nilsson, Edith Schallmeiner, Ola Söderberg, Johan Stenberg

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contribution

Abstract

A family of molecular tools will be described that taken together allow complex biological samples to be interrogated for large sets of target nucleic acid or protein molecules, extending down to even individual molecules. We have used the probes for single-molecule detection and counting in microscopic preparations and in microfabricated fluidic channels.

Original languageEnglish
Title of host publicationMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherTransducer Research Foundation
Pages1057-1059
Number of pages3
Volume1
ISBN (Print)0974361119, 9780974361116
Publication statusPublished - 2005
Event9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States
Duration: 9 Oct 200513 Oct 2005

Other

Other9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
CountryUnited States
CityBoston, MA
Period9/10/0513/10/05

Keywords

  • DNA microarrays
  • High-throughput genomics
  • Microfluidics
  • Molecular diagnostics
  • Molecular tools
  • Padlock probes
  • Proximity ligation
  • Rolling-circle amplification
  • Single-molecule detection

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  • Cite this

    Landegren, U., Banér, J., Dahl, F., Göransson, J., Gullberg, M., Gustafsdottir, S., ... Stenberg, J. (2005). Tools to study individual genes and proteins. In Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (Vol. 1, pp. 1057-1059). Transducer Research Foundation.