Topical negative pressure wound therapy

A review of its role and guidelines for its use in the management of acute wounds

Estas Bovill, Paul E. Banwell, Luc Teot, Elof Eriksson, Colin Song, Jim Mahoney, Ronny Gustafsson, Raymund Horch, Anand Deva, Ian Whitworth

Research output: Contribution to journalReview article

78 Citations (Scopus)


Over the past two decades, topical negative pressure (TNP) wound therapy has gained wide acceptance as a genuine strategy in the treatment algorithm for a wide variety of acute and chronic wounds. Although extensive experimental and clinical evidence exists to support its use and despite the recent emergence of randomised control trials, its role and indications have yet to be fully determined. This article provides a qualitative overview of the published literature appertaining to the use of TNP therapy in the management of acute wounds by an international panel of experts using standard methods of appraisal. Particular focus is applied to the use of TNP for the open abdomen, sternal wounds, lower limb trauma, burns and tissue coverage with grafts and dermal substitutes. We provide evidence-based recommendations for indications and techniques in TNP wound therapy and, where studies are insufficient, consensus on best practice.

Original languageEnglish
Pages (from-to)511-529
Number of pages19
JournalInternational Wound Journal
Issue number4
Publication statusPublished - Oct 2008
Externally publishedYes

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