Tour de Herpes: cycling through the life and biology of HSV-1

Christopher E. Denes, Roger D. Everett, Russell J. Diefenbach*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Citations (Scopus)


Herpes simplex virus type 1 (HSV-1) is a prevalent and important human pathogen that has been studied in a wide variety of contexts. This book provides protocols currently in use in leading laboratories in many fields of HSV-1 research. This introductory chapter gives a brief overview of HSV-1 biology and life cycle, covering basic aspects of virus structure, the prevalence of and diseases caused by the virus, replication in cultured cells, viral latency, antiviral defenses, and the mechanisms that the virus uses to counteract these defenses.

Original languageEnglish
Title of host publicationHerpes simplex virus
Subtitle of host publicationmethods and protocols
EditorsRussell J. Diefenbach, Cornel Fraefel
Place of PublicationNew York, NY
PublisherHumana Press Inc.
Number of pages30
ISBN (Electronic)9781493998142
ISBN (Print)9781493998135
Publication statusPublished - 1 Jan 2020

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029


  • Herpes simplex virus type 1
  • HSV-1 biology
  • HSV-1 life cycle
  • Nomenclature

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