Tour de Herpes: cycling through the life and biology of HSV-1

Christopher E. Denes, Roger D. Everett, Russell J. Diefenbach*

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    12 Citations (Scopus)


    Herpes simplex virus type 1 (HSV-1) is a prevalent and important human pathogen that has been studied in a wide variety of contexts. This book provides protocols currently in use in leading laboratories in many fields of HSV-1 research. This introductory chapter gives a brief overview of HSV-1 biology and life cycle, covering basic aspects of virus structure, the prevalence of and diseases caused by the virus, replication in cultured cells, viral latency, antiviral defenses, and the mechanisms that the virus uses to counteract these defenses.

    Original languageEnglish
    Title of host publicationHerpes simplex virus
    Subtitle of host publicationmethods and protocols
    EditorsRussell J. Diefenbach, Cornel Fraefel
    Place of PublicationNew York, NY
    PublisherHumana Press Inc.
    Number of pages30
    ISBN (Electronic)9781493998142
    ISBN (Print)9781493998135
    Publication statusPublished - 1 Jan 2020

    Publication series

    NameMethods in Molecular Biology
    ISSN (Print)1064-3745
    ISSN (Electronic)1940-6029


    • Herpes simplex virus type 1
    • HSV-1 biology
    • HSV-1 life cycle
    • Nomenclature


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