Towards novel genetic biocontrol for managing invasive rabbits in Australia

Kevin P. Oh; Sarah Topfer; Frances Zewe; Heng Lin Yeap; Madi Rutherford; Hugh Mason; Maria Jenckel; Rahul Rane; Tanja Strive

Towards novel genetic biocontrol for managing invasive rabbits in Australia

Kevin P. Oh, Sarah Topfer, Frances Zewe, Heng Lin Yeap, Madi Rutherford, Hugh Mason, Maria Jenckel, Rahul Rane, Tanja Strive

Applied BioSciences

Research output: Contribution to conference › Abstract › peer-review

Abstract

The European rabbit is an invasive pest in Australia, with damage to agriculture exceeding AU$200M annually, and negative impacts on at least 300 threatened native species. Whilst managers have achieved some notable success using viral biological controls, emerging resistance within rabbit populations has motivated a need for new technologies that are more efficient and humane. Leveraging recent advances in genome engineering and mammalian gene drives, we are developing the essential capabilities to develop and evaluate a safe, targeted, and efficient novel genetic biocontrol. Here we discuss our team’s recent progress in genome editing, assisted reproductive technologies, and population genetics to support gene drive research in rabbits.

Original language	English
Publication status	Published - 1 May 2024
Event	Genetic Biocontrol Gordon Research Conference, 2024: Enhancing Public Health, Food Security and Biodiversity - Barcelona, Spain Duration: 19 May 2024 → 24 May 2024

Conference

Conference	Genetic Biocontrol Gordon Research Conference, 2024
Abbreviated title	GRC 2024
Country/Territory	Spain
City	Barcelona
Period	19/05/24 → 24/05/24

Access to Document

http://hdl.handle.net/102.100.100/635306?index=1

Cite this

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title = "Towards novel genetic biocontrol for managing invasive rabbits in Australia",

abstract = "The European rabbit is an invasive pest in Australia, with damage to agriculture exceeding AU$200M annually, and negative impacts on at least 300 threatened native species. Whilst managers have achieved some notable success using viral biological controls, emerging resistance within rabbit populations has motivated a need for new technologies that are more efficient and humane. Leveraging recent advances in genome engineering and mammalian gene drives, we are developing the essential capabilities to develop and evaluate a safe, targeted, and efficient novel genetic biocontrol. Here we discuss our team{\textquoteright}s recent progress in genome editing, assisted reproductive technologies, and population genetics to support gene drive research in rabbits.",

author = "Oh, {Kevin P.} and Sarah Topfer and Frances Zewe and Yeap, {Heng Lin} and Madi Rutherford and Hugh Mason and Maria Jenckel and Rahul Rane and Tanja Strive",

year = "2024",

month = may,

day = "1",

language = "English",

note = "Genetic Biocontrol Gordon Research Conference, 2024 : Enhancing Public Health, Food Security and Biodiversity, GRC 2024 ; Conference date: 19-05-2024 Through 24-05-2024",

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T1 - Towards novel genetic biocontrol for managing invasive rabbits in Australia

AU - Oh, Kevin P.

AU - Topfer, Sarah

AU - Zewe, Frances

AU - Yeap, Heng Lin

AU - Rutherford, Madi

AU - Mason, Hugh

AU - Jenckel, Maria

AU - Rane, Rahul

AU - Strive, Tanja

PY - 2024/5/1

Y1 - 2024/5/1

N2 - The European rabbit is an invasive pest in Australia, with damage to agriculture exceeding AU$200M annually, and negative impacts on at least 300 threatened native species. Whilst managers have achieved some notable success using viral biological controls, emerging resistance within rabbit populations has motivated a need for new technologies that are more efficient and humane. Leveraging recent advances in genome engineering and mammalian gene drives, we are developing the essential capabilities to develop and evaluate a safe, targeted, and efficient novel genetic biocontrol. Here we discuss our team’s recent progress in genome editing, assisted reproductive technologies, and population genetics to support gene drive research in rabbits.

AB - The European rabbit is an invasive pest in Australia, with damage to agriculture exceeding AU$200M annually, and negative impacts on at least 300 threatened native species. Whilst managers have achieved some notable success using viral biological controls, emerging resistance within rabbit populations has motivated a need for new technologies that are more efficient and humane. Leveraging recent advances in genome engineering and mammalian gene drives, we are developing the essential capabilities to develop and evaluate a safe, targeted, and efficient novel genetic biocontrol. Here we discuss our team’s recent progress in genome editing, assisted reproductive technologies, and population genetics to support gene drive research in rabbits.

M3 - Abstract

T2 - Genetic Biocontrol Gordon Research Conference, 2024

Y2 - 19 May 2024 through 24 May 2024

ER -