Transcortical mixed aphasia due to cerebral infarction in left inferior frontal lobe and temporo-parietal lobe

S. Maeshima*, H. Toshiro, E. Sekiguchi, R. Okita, H. Yamaga, F. Ozaki, H. Moriwaki, T. Matsumoto, A. Ueyoshi, P. Roger

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

We present a case of transcortical mixed aphasia caused by a cerebral embolism. A 77-year-old right-handed man was admitted to our hospital with speech disturbance and a right hemianopia. His spontaneous speech was remarkably reduced, and object naming, word fluency, comprehension, reading and writing were all severely disturbed. However, repetition of phonemes and sentences and reading aloud were fully preserved. Although magnetic resonance imaging (MRI) showed cerebral infarcts in the left frontal and parieto-occipital lobe which included the inferior frontal gyrus and angular gyrus, single photon emission CT revealed a wider area of low perfusion over the entire left hemisphere except for part of the left perisylvian language areas. The amytal (Wada) test, which was performed via the left internal carotid artery, revealed that the left hemisphere was dominant for language. Hence, it appears that transcortical mixed aphasia may be caused by the isolation of perisylvian speech areas, even if there is a lesion in the inferior frontal gyrus, due to disconnection from surrounding areas.

Original languageEnglish
Pages (from-to)133-137
Number of pages5
JournalNeuroradiology
Volume44
Issue number2
DOIs
Publication statusPublished - 2002
Externally publishedYes

Keywords

  • Aphasia
  • Cerebral blood flow
  • Repetition
  • Speech area

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