Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for generalized anxiety disorder and comorbid disorders: a randomized controlled trial

B. F. Dear*, L. G. Staples, M. D. Terides, E. Karin, J. Zou, L. Johnston, M. Gandy, V. J. Fogliati, B. M. Wootton, P. M. McEvoy, N. Titov

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    99 Citations (Scopus)
    15 Downloads (Pure)

    Abstract

    Generalized anxiety disorder (GAD) can be treated effectively with either disorder-specific cognitive behavior therapy (DS-CBT) or transdiagnostic CBT (TD-CBT). The relative benefits of DS-CBT and TD-CBT for GAD and the relative benefits of delivering treatment in clinician guided (CG-CBT) and self-guided (SG-CBT) formats have not been examined. Participants with GAD (n= 338) were randomly allocated to receive an internet-delivered TD-CBT or DS-CBT intervention delivered in either CG-CBT or SG-CBT formats. Large reductions in symptoms of GAD (Cohen's d≥ 1.48; avg reduction ≥ 50%) and comorbid major depressive disorder (Cohen's d≥ 1.64; avg reduction ≥ 45%), social anxiety disorder (Cohen's d≥ 0.80; avg reduction ≥ 29%) and panic disorder (Cohen's d≥ 0.55; avg reduction ≥ 33%) were found across the conditions. No substantive differences were observed between DS-CBT and TD-CBT or CG-CBT and SG-CBT, highlighting the public health potential of carefully developed TD-CBT and SG-CBT.

    Original languageEnglish
    Pages (from-to)63-77
    Number of pages15
    JournalJournal of Anxiety Disorders
    Volume36
    DOIs
    Publication statusPublished - 1 Dec 2015

    Bibliographical note

    Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

    Keywords

    • Generalized anxiety disorder
    • Anxiety disorders
    • Treatment
    • Transdiagnostic
    • Disorder-specific
    • Self-guided
    • Clinician-guided
    • Internet
    • 24-Month follow-up
    • Randomized controlled trial

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