Transient storage of a tactile memory trace in primary somatosensory cortex

Justin A. Harris*, Carlo Miniussi, Irina M. Harris, Mathew E. Diamond

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    168 Citations (Scopus)

    Abstract

    Working memory is known to involve prefrontal cortex and posterior regions of association cortex (e.g., the inferior temporal lobes). Here, we investigate the potential role of primary somatosensory cortex (SI) in a working memory task with tactile stimuli. Subjects were required to compare the frequencies of two vibrations separated by a retention interval of 1500 msec. Their performance was significantly disrupted when we delivered a pulse of transcranial magnetic stimulation (TMS) to the contralateral SI early (300 or 600 msec) in the retention interval. TMS did not affect tactile working memory if delivered to contralateral SI late in the retention interval (at 900 or 1200 msec), nor did TMS affect performance if delivered to the ipsilateral SI at any time point. Primary sensory cortex thus seems to act not only as a center for on-line sensory processing but also as a transient storage site for information that contributes to working memory.

    Original languageEnglish
    Pages (from-to)8720-8725
    Number of pages6
    JournalJournal of Neuroscience
    Volume22
    Issue number19
    Publication statusPublished - 1 Oct 2002

    Keywords

    • Flutter vibration
    • Immediate memory
    • Somatosensory cortex
    • Somatotopic
    • Transcranial magnetic stimulation
    • Working memory

    Fingerprint

    Dive into the research topics of 'Transient storage of a tactile memory trace in primary somatosensory cortex'. Together they form a unique fingerprint.

    Cite this