TY - JOUR
T1 - Traumatic peripheral nerve injuries
T2 - Diagnosis and management
AU - Barnes, Stephanie L.
AU - Miller, Thomas A.
AU - Simon, Neil G.
PY - 2022/12/1
Y1 - 2022/12/1
N2 - Purpose of review: To review advances in the diagnostic evaluation and management of traumatic peripheral nerve injuries. Recent findings: Serial multimodal assessment of peripheral nerve injuries facilitates assessment of spontaneous axonal regeneration and selection of appropriate patients for early surgical intervention. Novel surgical and rehabilitative approaches have been developed to complement established strategies, particularly in the area of nerve grafting, targeted rehabilitation strategies and interventions to promote nerve regeneration. However, several management challenges remain, including incomplete reinnervation, traumatic neuroma development, maladaptive central remodeling and management of fatigue, which compromise functional recovery. Summary: Innovative approaches to the assessment and treatment of peripheral nerve injuries hold promise in improving the degree of functional recovery; however, this remains a complex and evolving area.
AB - Purpose of review: To review advances in the diagnostic evaluation and management of traumatic peripheral nerve injuries. Recent findings: Serial multimodal assessment of peripheral nerve injuries facilitates assessment of spontaneous axonal regeneration and selection of appropriate patients for early surgical intervention. Novel surgical and rehabilitative approaches have been developed to complement established strategies, particularly in the area of nerve grafting, targeted rehabilitation strategies and interventions to promote nerve regeneration. However, several management challenges remain, including incomplete reinnervation, traumatic neuroma development, maladaptive central remodeling and management of fatigue, which compromise functional recovery. Summary: Innovative approaches to the assessment and treatment of peripheral nerve injuries hold promise in improving the degree of functional recovery; however, this remains a complex and evolving area.
KW - nerve imaging
KW - nerve injury
KW - nerve transfer
KW - peripheral nerve trauma
KW - rehabilitation
UR - http://www.scopus.com/inward/record.url?scp=85141553951&partnerID=8YFLogxK
U2 - 10.1097/WCO.0000000000001116
DO - 10.1097/WCO.0000000000001116
M3 - Review article
C2 - 36367041
AN - SCOPUS:85141553951
SN - 1350-7540
VL - 35
SP - 718
EP - 727
JO - Current Opinion in Neurology
JF - Current Opinion in Neurology
IS - 6
ER -