Treatment of excitotoxicity-related conditions

Lars Ittner; Yazi Diana Ke

Treatment of excitotoxicity-related conditions

Lars Ittner (Inventor), Yazi Diana Ke (Inventor)

Research output: Patent

Abstract

Disclosed herein are methods for treating or preventing an excitotoxicity-related condition, optionally a condition associated with seizures and/or resulting from or associated with a cerebral ischemic event, comprising administering to a subject in need an effective amount of an inhibitor of Lim-domain kinase 1 (LIMK1). Also provided are methods for treating or preventing seizures and for reducing excitotoxicity in neurons and/or protecting neurons from excitotoxicity.

Original language	English
Patent number	WO2021056072
IPC	A61P 25/ 08 A I,A61K 31/519 2006.1,A61P 25/00 2006.1
Priority date	25/09/19
Filing date	25/09/20
Publication status	Published - 1 Apr 2021

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3 Patent

Treatment of excitotoxicity-related conditions
Ittner, L. (Inventor) & Ke, Y. D. (Inventor), 19 May 2022, IPC No. A61P 25/ 08 A I, A61K 31/519, A61P 25/00, Patent No. AU2020354786, 25 Sept 2020, Priority date 25 Sept 2020, Priority No. AU2019903588
Research output: Patent

Open Access
Treatment of excitotoxicity-related conditions
Ittner, L. (Inventor) & Ke, Y. D. (Inventor), 15 Sept 2022, IPC No. A61P 25/ 08 A I, A61K 31/519, Patent No. US2022288081, 25 Sept 2020, Priority date 25 Sept 2019, Priority No. AU2019903588
Research output: Patent

Open Access
Treatment of excitotoxicity-related conditions
Ittner, L. (Inventor) & Ke, Y. D. (Inventor), 3 Aug 2022, IPC No. A61P 25/ 08 A I, A61K 31/519, A61P 25/00, A61K 45/06, A61P 9/10, A61P 27/06, Patent No. EP4034125, Priority date 25 Sept 2019, Priority No. AU2019903588
Research output: Patent

Open Access

Cite this

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title = "Treatment of excitotoxicity-related conditions",

abstract = "Disclosed herein are methods for treating or preventing an excitotoxicity-related condition, optionally a condition associated with seizures and/or resulting from or associated with a cerebral ischemic event, comprising administering to a subject in need an effective amount of an inhibitor of Lim-domain kinase 1 (LIMK1). Also provided are methods for treating or preventing seizures and for reducing excitotoxicity in neurons and/or protecting neurons from excitotoxicity.",

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year = "2021",

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AU - Ke, Yazi Diana

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AB - Disclosed herein are methods for treating or preventing an excitotoxicity-related condition, optionally a condition associated with seizures and/or resulting from or associated with a cerebral ischemic event, comprising administering to a subject in need an effective amount of an inhibitor of Lim-domain kinase 1 (LIMK1). Also provided are methods for treating or preventing seizures and for reducing excitotoxicity in neurons and/or protecting neurons from excitotoxicity.

M3 - Patent

M1 - WO2021056072

Y2 - 2020/09/25

ER -

Treatment of excitotoxicity-related conditions

Abstract

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