Tunicamycin‐resistant mutants of Bacillus amyloliquefaciens are deficient in amylase, protease and penicillinase synthesis and have altered sensitivity to antibiotics and autolysis

F. F. Dias*, M. ‐K G Shaikh, Y. B. Bhatt, D. C. Modi, V. R. Subramanyam

*Corresponding author for this work

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Mutants of Bacillus amyloliquefaciens resistant to at least 10 μg/ml of tunicamycin were isolated and shown to be pleiotropic. The mutants were more resistant to streptomycin, chloramphenicol, kanamycin and neomycin than was the parent strain but less resistant to penicillin G and tetracycline. They were more autolytic, presumably due to an altered cell wall. The mutants produced reduced levels of amylase, penicillinase and both metal and serine protease besides having an enhanced sporulation frequency and being more motile.

Original languageEnglish
Pages (from-to)271-275
Number of pages5
JournalJournal of Applied Bacteriology
Volume60
Issue number4
DOIs
Publication statusPublished - 1986
Externally publishedYes

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