Unconfined compression of white matter

Shaokoon Cheng, Lynne E. Bilston*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

154 Citations (Scopus)

Abstract

The porous properties of brain tissue are important for understanding normal and abnormal cerebrospinal fluid flow in the brain. In this study, a poroviscoelastic model was fitted to the stress relaxation response of white matter in unconfined compression performed under a range of low strain rates. A set of experiments was also performed on the tissue samples using a no-slip boundary condition. Results from these experiments demonstrated that the rheological response of the white matter is primarily governed by the intrinsic viscoelastic properties of the solid phase. The permeability of white matter was found to be of the order of 10-12 m4/Ns.

Original languageEnglish
Pages (from-to)117-124
Number of pages8
JournalJournal of Biomechanics
Volume40
Issue number1
DOIs
Publication statusPublished - 2007
Externally publishedYes

Keywords

  • Brain tissues
  • Poroviscoelastic
  • Stress relaxation
  • Unconfined compression
  • White matter

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