Use of the CogState brief battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study

Yen Ying Lim; Kathryn A. Ellis; Karra Harrington; David Ames; Ralph N. Martins; Colin L. Masters; Christopher Rowe; Greg Savage; Cassandra Szoeke; David Darby; Paul Maruff; The AIBL Research Group

doi:10.1080/13803395.2011.643227

Use of the CogState brief battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study

Yen Ying Lim^*, Kathryn A. Ellis, Karra Harrington, David Ames, Ralph N. Martins, Colin L. Masters, Christopher Rowe, Greg Savage, Cassandra Szoeke, David Darby, Paul Maruff, The AIBL Research Group

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

120 Citations (Scopus)

Abstract

The aim of this study was to validate the CogState Brief Battery, which assesses psychomotor, attentional, working memory, and visual learning functions, in healthy older people and in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD), enrolled in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. In healthy older adults, weak relationships between demographic variables (e.g., education, depression) and cognitive performance were observed. In AD and MCI groups, the magnitude of impairment was greatest for tasks of working memory and memory, with a negative influence of apolipoprotein E ε4 status on learning but not working memory. These results suggest that the CogState Brief Battery can be used to screen for AD-related cognitive changes.

Original language	English
Pages (from-to)	345-358
Number of pages	14
Journal	Journal of Clinical and Experimental Neuropsychology
Volume	34
Issue number	4
DOIs	https://doi.org/10.1080/13803395.2011.643227
Publication status	Published - 2012

Keywords

Alzheimer’s disease
CogState
Australian imaging
Biomarkers and Lifestyle study
Apolipoprotein E ε4
Cognitive testing

Access to Document

10.1080/13803395.2011.643227

Cite this

Lim, Y. Y., Ellis, K. A., Harrington, K., Ames, D., Martins, R. N., Masters, C. L., Rowe, C., Savage, G., Szoeke, C., Darby, D., Maruff, P., & The AIBL Research Group (2012). Use of the CogState brief battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. Journal of Clinical and Experimental Neuropsychology, 34(4), 345-358. https://doi.org/10.1080/13803395.2011.643227

@article{60eae2ee8d5d43a4b25ac73e4358ac16,

title = "Use of the CogState brief battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study",

abstract = "The aim of this study was to validate the CogState Brief Battery, which assesses psychomotor, attentional, working memory, and visual learning functions, in healthy older people and in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD), enrolled in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. In healthy older adults, weak relationships between demographic variables (e.g., education, depression) and cognitive performance were observed. In AD and MCI groups, the magnitude of impairment was greatest for tasks of working memory and memory, with a negative influence of apolipoprotein E ε4 status on learning but not working memory. These results suggest that the CogState Brief Battery can be used to screen for AD-related cognitive changes.",

keywords = "Alzheimer{\textquoteright}s disease, CogState, Australian imaging, Biomarkers and Lifestyle study, Apolipoprotein E ε4, Cognitive testing",

author = "Lim, {Yen Ying} and Ellis, {Kathryn A.} and Karra Harrington and David Ames and Martins, {Ralph N.} and Masters, {Colin L.} and Christopher Rowe and Greg Savage and Cassandra Szoeke and David Darby and Paul Maruff and {The AIBL Research Group}",

year = "2012",

doi = "10.1080/13803395.2011.643227",

language = "English",

volume = "34",

pages = "345--358",

journal = "Journal of Clinical and Experimental Neuropsychology",

issn = "1380-3395",

publisher = "Taylor & Francis",

number = "4",

}

Lim, YY, Ellis, KA, Harrington, K, Ames, D, Martins, RN, Masters, CL, Rowe, C, Savage, G, Szoeke, C, Darby, D, Maruff, P & The AIBL Research Group 2012, 'Use of the CogState brief battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study', Journal of Clinical and Experimental Neuropsychology, vol. 34, no. 4, pp. 345-358. https://doi.org/10.1080/13803395.2011.643227

Use of the CogState brief battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. / Lim, Yen Ying; Ellis, Kathryn A.; Harrington, Karra et al.
In: Journal of Clinical and Experimental Neuropsychology, Vol. 34, No. 4, 2012, p. 345-358.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Use of the CogState brief battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study

AU - Lim, Yen Ying

AU - Ellis, Kathryn A.

AU - Harrington, Karra

AU - Ames, David

AU - Martins, Ralph N.

AU - Masters, Colin L.

AU - Rowe, Christopher

AU - Savage, Greg

AU - Szoeke, Cassandra

AU - Darby, David

AU - Maruff, Paul

AU - The AIBL Research Group

PY - 2012

Y1 - 2012

N2 - The aim of this study was to validate the CogState Brief Battery, which assesses psychomotor, attentional, working memory, and visual learning functions, in healthy older people and in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD), enrolled in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. In healthy older adults, weak relationships between demographic variables (e.g., education, depression) and cognitive performance were observed. In AD and MCI groups, the magnitude of impairment was greatest for tasks of working memory and memory, with a negative influence of apolipoprotein E ε4 status on learning but not working memory. These results suggest that the CogState Brief Battery can be used to screen for AD-related cognitive changes.

AB - The aim of this study was to validate the CogState Brief Battery, which assesses psychomotor, attentional, working memory, and visual learning functions, in healthy older people and in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD), enrolled in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. In healthy older adults, weak relationships between demographic variables (e.g., education, depression) and cognitive performance were observed. In AD and MCI groups, the magnitude of impairment was greatest for tasks of working memory and memory, with a negative influence of apolipoprotein E ε4 status on learning but not working memory. These results suggest that the CogState Brief Battery can be used to screen for AD-related cognitive changes.

KW - Alzheimer’s disease

KW - CogState

KW - Australian imaging

KW - Biomarkers and Lifestyle study

KW - Apolipoprotein E ε4

KW - Cognitive testing

UR - http://www.scopus.com/inward/record.url?scp=84859204740&partnerID=8YFLogxK

U2 - 10.1080/13803395.2011.643227

DO - 10.1080/13803395.2011.643227

M3 - Article

C2 - 22248010

AN - SCOPUS:84859204740

SN - 1380-3395

VL - 34

SP - 345

EP - 358

JO - Journal of Clinical and Experimental Neuropsychology

JF - Journal of Clinical and Experimental Neuropsychology

IS - 4

ER -

Use of the CogState brief battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this