Use of the Fisher Information Matrix to optimize the acquisition protocol for a D-SPECT system

Niccolo Fuin, Stefano Pedemonte, Simon Arridge, Sebastien Ourselin, Brian F. Hutton

    Research output: Chapter in Book/Report/Conference proceedingConference proceeding contribution

    Abstract

    The design of the D-SPECT system is based on compact CZT solid state detectors units that permit movements that would not be achievable with conventional gamma cameras. This new design permits to overcome some inherent SPECT limitations allowing for a region-centric acquisition. By choosing to spend more time directing the detector heads towards a region of interest (ROI), one can allocate more time to collect data from this region at the expense of collecting fewer data from less important regions. However, changing the detector angular movements allowing for a non uniform scanning pattern, the interdependence in the information changes and the D-SPECT system response may be highly shift-variant. In order to be able to compare a set of candidate scanning patterns (for a given activity distribution) a method is needed, that quantifies the information gain.

    Original languageEnglish
    Title of host publication2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2012
    Pages2137-2142
    Number of pages6
    DOIs
    Publication statusPublished - 2012
    Event2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2012 - Anaheim, CA, United States
    Duration: 29 Oct 20123 Nov 2012

    Other

    Other2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2012
    CountryUnited States
    CityAnaheim, CA
    Period29/10/123/11/12

    Keywords

    • D-SPECT
    • Emission Tomography
    • Fisher Information
    • Reconstruction Image Quality
    • System Design

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