Using genome-enabled technologies to address allergens in seeds of crop plants: legumes as a case study

Lena Y. C. Soo, Nicole E. Walczyk, Penelope M. C. Smith

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

In this chapter, we discuss how genome-enabled technologies have improved identification of legume seed allergens and are contributing to the development of hypoallergenic legume crops. We show how proteomic identification of allergens will be driven by the availability of plant genomes. The expression of the major allergens can be reduced or eliminated by gene silencing, mutation, or genome editing. The limitation of these technologies to agricultural performance and food quality, and the clinical consequences of modified food products are described.
Original languageEnglish
Title of host publicationSeed development
Subtitle of host publicationOMICS technologies toward improvement of seed quality and crop yield : OMICS in seed biology
EditorsGanesh K. Agrawal, Randeep Rakwal
Place of PublicationDordrecht ; London
PublisherSpringer, Springer Nature
Pages503-525
Number of pages23
ISBN (Print)9789400747494
DOIs
Publication statusPublished - 2012

Keywords

  • Legumes
  • Seed allergens
  • Food allergy
  • Hypoallergenic
  • Gene silencing
  • Mutagenesis

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