Ventricular volume in infantile hydrocephalus and its relationship to intracranial pressure and cerebrospinal fluid clearance before and after treatment: A preliminary study

W. J. Maixner, M. K. Morgan, M. Besser, I. H. Johnston*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

The present study examines ventricular volume before and after shunting in 16 infants with hydrocephalus and mixed aetiology and relates this parameter to rates of cerebrospinal fluid clearance, intracranial pressure and outcome. Following treatment all patients showed reduction in intracranial pressure and amelioration of the clinical manifestations of hydrocephalus. Nevertheless, 4 patients showed persistence of marked venlriculomegaly. 4 had moderate ventricular enlargement, while 8 showed small or normal ventricles. Although the series was small there appeared to be a clear correlation between persistent ventriculomegaly. poor cerebrospinal fluid clearance and poor outcome despite reduction in intracranial pressure. The question is raised as to whether pressure-determined cerebrospinal fluid drainage provides optimum treatment of hydrocephalus in infants given the particular physical characteristics pertaining to the non-rigid cranium.

Original languageEnglish
Pages (from-to)191-196
Number of pages6
JournalPediatric Neurosurgery
Volume16
Issue number4-5
DOIs
Publication statusPublished - 1990
Externally publishedYes

Keywords

  • Cerebrospinal fluid clearance
  • Infantile hydrocephalus
  • Intracranial pressure
  • Outcome
  • Ventricular volume

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