PET studies have shown an association between changes in blood flow in the insular cortex and verbal memory. This study compared verbal memory profiles between a group of four right handed patients with right insular infarction and a group of six right handed patients with left insular infarction. Patient groups were comparable in age, education, and sex. Patients were administered memory tests about 4-8 weeks poststroke. Patients with left insular lesions showed significantly poorer immediate and delayed verbal memory as measured by story A of the WMS-R logical memory I (t = -2.73, p < 0.03) and logical memory II (t = -4.1, p < 0.004) subtests as well as the CERAD word list memory (delayed recall) (t = -2.4, p < 0.05). These findings indicate that left insular damage is associated with poorer performance on verbal memory tasks. The findings suggest that the insula may be part of a functional network that mediates verbal memory.
|Number of pages||3|
|Journal||Journal of Neurology Neurosurgery and Psychiatry|
|Publication status||Published - Oct 1999|