Very minimal fluence photodynamic therapy for chronic central serous chorioretinopathy

Andrea L. Butler; Adrian T. Fung; Andrew B. Merkur; David A. Albiani; Farzin Forooghian

doi:10.1016/j.jcjo.2011.12.020

Very minimal fluence photodynamic therapy for chronic central serous chorioretinopathy

Andrea L. Butler, Adrian T. Fung, Andrew B. Merkur, David A. Albiani, Farzin Forooghian^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Objective: To describe the safety and efficacy of very minimal fluence photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). Design: Retrospective case series. Participants: Five patients with chronic CSC. Two had previously failed alternative therapies, and one was taking concomitant corticosteroids. Methods: Patients were treated with very minimal fluence PDT (12 J/cm², 150 mW/cm², for 80 seconds). Median follow-up time after PDT was 100 days (range, 51 to 154). Results: All patients experienced an improvement in visual acuity and symptoms, as well as complete resolution of subretinal fluid. Conclusions: Very minimal fluence PDT appears to be a safe and effective treatment for chronic CSC. Based on these preliminary findings, a randomized controlled trial is warranted.

Original language	English
Pages (from-to)	42-44
Number of pages	3
Journal	Canadian Journal of Ophthalmology
Volume	47
Issue number	1
DOIs	https://doi.org/10.1016/j.jcjo.2011.12.020
Publication status	Published - 2012
Externally published	Yes

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10.1016/j.jcjo.2011.12.020

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title = "Very minimal fluence photodynamic therapy for chronic central serous chorioretinopathy",

abstract = "Objective: To describe the safety and efficacy of very minimal fluence photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). Design: Retrospective case series. Participants: Five patients with chronic CSC. Two had previously failed alternative therapies, and one was taking concomitant corticosteroids. Methods: Patients were treated with very minimal fluence PDT (12 J/cm2, 150 mW/cm2, for 80 seconds). Median follow-up time after PDT was 100 days (range, 51 to 154). Results: All patients experienced an improvement in visual acuity and symptoms, as well as complete resolution of subretinal fluid. Conclusions: Very minimal fluence PDT appears to be a safe and effective treatment for chronic CSC. Based on these preliminary findings, a randomized controlled trial is warranted.",

author = "Butler, {Andrea L.} and Fung, {Adrian T.} and Merkur, {Andrew B.} and Albiani, {David A.} and Farzin Forooghian",

year = "2012",

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language = "English",

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T1 - Very minimal fluence photodynamic therapy for chronic central serous chorioretinopathy

AU - Butler, Andrea L.

AU - Fung, Adrian T.

AU - Merkur, Andrew B.

AU - Albiani, David A.

AU - Forooghian, Farzin

PY - 2012

Y1 - 2012

N2 - Objective: To describe the safety and efficacy of very minimal fluence photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). Design: Retrospective case series. Participants: Five patients with chronic CSC. Two had previously failed alternative therapies, and one was taking concomitant corticosteroids. Methods: Patients were treated with very minimal fluence PDT (12 J/cm2, 150 mW/cm2, for 80 seconds). Median follow-up time after PDT was 100 days (range, 51 to 154). Results: All patients experienced an improvement in visual acuity and symptoms, as well as complete resolution of subretinal fluid. Conclusions: Very minimal fluence PDT appears to be a safe and effective treatment for chronic CSC. Based on these preliminary findings, a randomized controlled trial is warranted.

AB - Objective: To describe the safety and efficacy of very minimal fluence photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC). Design: Retrospective case series. Participants: Five patients with chronic CSC. Two had previously failed alternative therapies, and one was taking concomitant corticosteroids. Methods: Patients were treated with very minimal fluence PDT (12 J/cm2, 150 mW/cm2, for 80 seconds). Median follow-up time after PDT was 100 days (range, 51 to 154). Results: All patients experienced an improvement in visual acuity and symptoms, as well as complete resolution of subretinal fluid. Conclusions: Very minimal fluence PDT appears to be a safe and effective treatment for chronic CSC. Based on these preliminary findings, a randomized controlled trial is warranted.

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Very minimal fluence photodynamic therapy for chronic central serous chorioretinopathy

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