Abstract
An increasing number of viruses have been shown to require the microtubule cytoskeleton for entry into and egress from the infected host cell. The transport of virions and/or their components along microtubules depends on the host cell molecular motors dynein and kinesin. This review highlights the known interactions involving viral proteins and the subunits of dynein/kinesin. The biological relevance of these interactions are discussed in the context of the viral replication cycle.
Original language | English |
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Pages (from-to) | 13-21 |
Journal | Current Topics in Biochemical Research |
Volume | 10 |
Issue number | 1 |
Publication status | Published - 2008 |
Externally published | Yes |
Keywords
- viral transport
- Dyneins
- Kinesin
- Microtubule