Visual evoked potential recording in rodents

Yuyi You*, Alexander Klistorner, Stuart L. Graham

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    4 Citations (Scopus)


    The visual evoked potential (VEP) is an electronic potential recorded from the visual cortex in response to a visual stimulus. It provides a means to examine the function of the visual pathway from the retina to the occipital cortex. The most common animals employed in VEP laboratory studies are rats. In this chapter, we describe the basic 'flash VEP' recording protocol in rodents and discuss the practical aspects of the preparation including anaesthesia methods, electrode configuration, stimulus design, dark adaptation, filter settings and signal sampling with the authors' personal experience. We also review the recent use of the VEP in laboratory researches in several optic nerve disease models, including glaucoma, ischemic optic neuropathy and optic neuritis.

    Original languageEnglish
    Title of host publicationStimulation and Inhibition of Neurons
    EditorsPaul M. Pilowsky, Melissa M.J. Farnham, Angelina Y. Fong
    Place of PublicationNew York
    PublisherHumana Press
    Number of pages11
    ISBN (Electronic)9781627032339
    ISBN (Print)9781627032322
    Publication statusPublished - 2013

    Publication series

    PublisherHumana Press
    ISSN (Print)0893-2336
    ISSN (Electronic)1940-6045


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