Wet Lab Accelerator: a web-based application democratizing laboratory automation for synthetic biology

Maxwell Bates, Aaron J. Berliner, Joe Lachoff, Paul R. Jaschke, Eli S. Groban

    Research output: Contribution to journalArticlepeer-review

    26 Citations (Scopus)
    158 Downloads (Pure)

    Abstract

    Wet Lab Accelerator (WLA) is a cloud-based tool that allows a scientist to conduct biology via robotic control without the need for any programming knowledge. A drag and drop interface provides a convenient and user-friendly method of generating biological protocols. Graphically developed protocols are turned into programmatic instruction lists required to conduct experiments at the cloud laboratory Transcriptic. Prior to the development of WLA, biologists were required to write in a programming language called “Autoprotocol” in order to work with Transcriptic. WLA relies on a new abstraction layer we call “Omniprotocol” to convert the graphical experimental description into lower level Autoprotocol language, which then directs robots at Transcriptic. While WLA has only been tested at Transcriptic, the conversion of graphically laid out experimental steps into Autoprotocol is generic, allowing extension of WLA into other cloud laboratories in the future. WLA hopes to democratize biology by bringing automation to general biologists.
    Original languageEnglish
    Pages (from-to)167-171
    Number of pages5
    JournalACS Synthetic Biology
    Volume6
    Issue number1
    DOIs
    Publication statusPublished - 20 Jan 2017

    Bibliographical note

    Copyright American Chemical Society 2017. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

    Keywords

    • automation
    • autoprotocol
    • cloud-lab
    • democratization
    • scientific reproducibility
    • standardization
    • synthetic biology
    • Democratization
    • Automation
    • Scientific reproducibility
    • Standardization
    • Cloud-lab
    • Autoprotocol
    • Synthetic biology

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