Research on vulnerable consumers remains unfailing in macromarketing and social marketing. Yet it is unclear how to operationalize the vulnerable consumers by demographics and further to this it is rarely touched how the vulnerable consumers defined by different measures make decision when choosing the place to shop especially in pharmacy retailing sector. The authors conduct a comparative study of variously-defined vulnerable consumers for their shopping store types in an urban Chinese city to investigate how people with distinct backgrounds develop their decision making rules and choose different types of retail pharmacies. This paper casts light on customer heterogeneity associated with different dimensions of vulnerability by using consumer demographics, and indicates that four dimensions of vulnerability exist as cognitive capability, social relations, behaviors, and the institutional protection in health-related sector. These four aspects of vulnerability play a significant role in identifying different shop selection patterns. Findings suggest that efforts to boost store patronage targeting on various consumer groups should have different strategies to reach consumers' mindsets.